rs10793726

This variant is located in the DSTYK gene.

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GWAS Catalog Trait Associations (5)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

C-type lectin domain family 1 member B amount

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.06
p 8.0e-13
N 47,745
Large GWAS
European

gamma-enolase measurement

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.06
p 4.0e-12
N 47,745
Large GWAS
European

level of serine/threonine-protein kinase STK11 in blood

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.06
p 7.0e-12
N 47,745
Large GWAS
European

Dupuytren Contracture

Riesmeijer SA et al. “A genome-wide association meta-analysis implicates Hedgehog and Notch signaling in Dupuytren's disease.” Nature Communications 15(1):199 (2024)
Allele T
OR 0.20
p 6.0e-9
N 58,343
Meta-analysisLarge GWAS
European

About DSTYK

This gene encodes a dual serine/threonine and tyrosine protein kinase which is expressed in multiple tissues. It is thought to function as a regulator of cell death. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]

View all DSTYK variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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