Trait
SNPs associated with Dupuytren Contracture
126 genetic variants across 24 genes have been associated with Dupuytren Contracture in published research. Key genes include AFAP1, ANTXR1, ATL1.
Associated variants126 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs2044830 | — | GWAS association (p=2.0e-176) | Meta-analysis |
| rs9626908 | — | GWAS association (p=5.0e-103) | Meta-analysis |
| rs2598100 | EPDR1 | GWAS association (p=1.0e-102) | Meta-analysis |
| rs2472141 | — | GWAS association (p=1.0e-85) | Meta-analysis |
| rs11672486 | DUXA | GWAS association (p=5.0e-60) | Meta-analysis |
| rs648596 | — | GWAS association (p=3.0e-48) | Meta-analysis |
| rs2162353 | — | GWAS association (p=3.0e-43) | Meta-analysis |
| rs12353046 | — | GWAS association (p=3.0e-42) | Meta-analysis |
| rs11665156 | RAB31 | GWAS association (p=3.0e-35) | Meta-analysis |
| rs17238923 | — | GWAS association (p=5.0e-32) | Meta-analysis |
| rs112116858 | — | GWAS association (p=1.0e-29) | Meta-analysis |
| rs7537281 | — | GWAS association (p=5.0e-29) | Meta-analysis |
| rs10100769 | — | GWAS association (p=5.0e-27) | Meta-analysis |
| rs12441312 | — | GWAS association (p=1.0e-26) | Meta-analysis |
| rs1042704 | MMP14 | GWAS association (p=3.0e-26) | Meta-analysis |
| rs12481661 | — | GWAS association (p=3.0e-25) | Meta-analysis |
| rs8032158 | NEDD4 | GWAS association (p=2.0e-24) | Meta-analysis |
| rs73818546 | — | GWAS association (p=7.0e-23) | Meta-analysis |
| rs58716951 | — | GWAS association (p=7.0e-22) | Meta-analysis |
| rs145039496 | WNT7B | GWAS association (p=9.0e-22) | Meta-analysis |
| rs28755830 | — | GWAS association (p=7.0e-21) | Meta-analysis |
| rs62443137 | — | GWAS association (p=5.0e-20) | Meta-analysis |
| rs1649199 | FGFR2 | GWAS association (p=6.0e-20) | Meta-analysis |
| rs7816361 | — | GWAS association (p=9.0e-20) | Meta-analysis |
| rs149796768 | — | GWAS association (p=1.0e-19) | Meta-analysis |
| rs17791680 | — | GWAS association (p=3.0e-19) | Meta-analysis |
| rs1965670 | — | GWAS association (p=1.0e-18) | Meta-analysis |
| rs9429893 | — | GWAS association (p=4.0e-18) | Meta-analysis |
| rs142243039 | — | GWAS association (p=1.0e-17) | Meta-analysis |
| rs77660995 | — | GWAS association (p=2.0e-17) | Meta-analysis |
| rs11200062 | — | GWAS association (p=2.0e-17) | Meta-analysis |
| rs366905 | — | GWAS association (p=1.0e-16) | Meta-analysis |
| rs11126214 | ANTXR1 | GWAS association (p=2.0e-16) | Meta-analysis |
| rs17573837 | ATXN10 | GWAS association (p=4.0e-16) | Meta-analysis |
| rs4942308 | — | GWAS association (p=2.0e-15) | Meta-analysis |
| rs75306755 | — | GWAS association (p=2.0e-14) | Meta-analysis |
| rs247436 | CFDP1 | GWAS association (p=3.0e-14) | Meta-analysis |
| rs78030362 | — | GWAS association (p=3.0e-14) | Meta-analysis |
| rs9770861 | — | GWAS association (p=1.0e-13) | Meta-analysis |
| rs72711557 | — | GWAS association (p=3.0e-13) | Meta-analysis |
| rs12881869 | — | GWAS association (p=5.0e-13) | Meta-analysis |
| rs10264803 | — | GWAS association (p=5.0e-13) | Meta-analysis |
| rs12442366 | — | GWAS association (p=6.0e-13) | Meta-analysis |
| rs6977665 | — | GWAS association (p=7.0e-13) | Meta-analysis |
| rs34412930 | — | GWAS association (p=8.0e-13) | Meta-analysis |
| rs38896 | — | GWAS association (p=8.0e-13) | Meta-analysis |
| rs10125663 | — | GWAS association (p=9.0e-13) | Meta-analysis |
| rs62524109 | — | GWAS association (p=1.0e-12) | Meta-analysis |
| rs73130881 | — | GWAS association (p=3.0e-12) | Meta-analysis |
| rs117707689 | — | GWAS association (p=9.0e-12) | Meta-analysis |
| rs77727254 | — | GWAS association (p=1.0e-11) | Meta-analysis |
| rs56098053 | LPP | GWAS association (p=1.0e-11) | Meta-analysis |
| rs10089785 | — | GWAS association (p=1.0e-11) | Meta-analysis |
| rs28522005 | — | GWAS association (p=2.0e-11) | Meta-analysis |
| rs117999064 | — | GWAS association (p=2.0e-11) | Meta-analysis |
| rs11743708 | — | GWAS association (p=2.0e-11) | Meta-analysis |
| rs181089987 | — | GWAS association (p=3.0e-11) | Meta-analysis |
| rs6462772 | — | GWAS association (p=4.0e-11) | Meta-analysis |
| rs4669784 | — | GWAS association (p=4.0e-11) | Meta-analysis |
| rs61092548 | — | GWAS association (p=1.0e-10) | Meta-analysis |
| rs28363932 | — | GWAS association (p=1.0e-10) | Meta-analysis |
| rs6472419 | C8orf34 | GWAS association (p=1.0e-10) | Meta-analysis |
| rs10174596 | — | GWAS association (p=2.0e-10) | Meta-analysis |
| rs57082097 | — | GWAS association (p=3.0e-10) | Meta-analysis |
| rs7307913 | — | GWAS association (p=9.0e-10) | Meta-analysis |
| rs73214051 | — | GWAS association (p=1.0e-09) | Meta-analysis |
| rs11581010 | MTOR | GWAS association (p=2.0e-09) | Meta-analysis |
| rs16988531 | — | GWAS association (p=4.0e-09) | Meta-analysis |
| rs10793726 | DSTYK | GWAS association (p=6.0e-09) | Meta-analysis |
| rs34203781 | — | GWAS association (p=9.0e-09) | Meta-analysis |
| rs1398882 | — | GWAS association (p=1.0e-08) | Meta-analysis |
| rs34810955 | — | GWAS association (p=1.0e-08) | Meta-analysis |
| rs10831757 | — | GWAS association (p=2.0e-08) | Meta-analysis |
| rs235931 | — | GWAS association (p=3.0e-08) | Meta-analysis |
| rs74516628 | — | GWAS association (p=3.0e-08) | Meta-analysis |
| rs886423 | — | GWAS association (p=3.0e-08) | Meta-analysis |
| rs71325072 | — | GWAS association (p=4.0e-08) | Meta-analysis |
| rs10453460 | — | GWAS association (p=9.9e-324) | Major Consortium Study |
| rs659430 | — | GWAS association (p=4.0e-62) | Major Consortium Study |
| rs11672517 | DUXA | GWAS association (p=1.0e-41) | Major Consortium Study |
| rs443680 | — | GWAS association (p=1.0e-36) | Major Consortium Study |
| rs28971325 | WNT7B | GWAS association (p=1.0e-34) | Major Consortium Study |
| rs10809657 | — | GWAS association (p=5.0e-28) | Major Consortium Study |
| rs12594617 | — | GWAS association (p=1.0e-20) | Major Consortium Study |
| rs6067835 | — | GWAS association (p=5.0e-20) | Major Consortium Study |
| rs7659911 | — | GWAS association (p=3.0e-19) | Major Consortium Study |
| rs17102363 | — | GWAS association (p=4.0e-19) | Major Consortium Study |
| rs9330392 | — | GWAS association (p=5.0e-17) | Major Consortium Study |
| rs140287116 | PRKN | GWAS association (p=1.0e-16) | Major Consortium Study |
| rs11802513 | — | GWAS association (p=5.0e-16) | Major Consortium Study |
| rs12481155 | — | GWAS association (p=9.0e-16) | Major Consortium Study |
| rs7018405 | — | GWAS association (p=5.0e-15) | Major Consortium Study |
| rs9923834 | CHST6 | GWAS association (p=1.0e-14) | Major Consortium Study |
| rs10226248 | — | GWAS association (p=8.0e-14) | Major Consortium Study |
| rs3851294 | DSTYK | GWAS association (p=2.0e-13) | Major Consortium Study |
| rs553045271 | — | GWAS association (p=7.0e-13) | Major Consortium Study |
| rs6850654 | AFAP1 | GWAS association (p=9.0e-13) | Major Consortium Study |
| rs1032466 | ATL1 | GWAS association (p=1.0e-12) | Major Consortium Study |
| rs1811475 | PTK2 | GWAS association (p=3.0e-12) | Major Consortium Study |
| rs79495111 | — | GWAS association (p=3.0e-12) | Major Consortium Study |
Showing the top 100 of 126 variants by evidence strength.
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.