rs145039496
This is a intron variant variant in the WNT7B gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
Dupuytren Contracture
Riesmeijer SA et al. “A genome-wide association meta-analysis implicates Hedgehog and Notch signaling in Dupuytren's disease.” Nature Communications 15(1):199 (2024)
Allele T
OR 0.56
p 9.0e-22
N 58,343
Meta-analysisLarge GWAS
European
About WNT7B
This gene is a member of the WNT gene family, which consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Among members of the human WNT family, this gene product is most similar to WNT7A protein. [provided by RefSeq, Oct 2008]
View all WNT7B variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
Community Wiki
No community notes yet for this variant. Sign in to start one.
Comments
Sign in to join the discussion.
Loading comments…