rs11665156
This is a intron variant variant in the RAB31 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
Dupuytren Contracture
Riesmeijer SA et al. “A genome-wide association meta-analysis implicates Hedgehog and Notch signaling in Dupuytren's disease.” Nature Communications 15(1):199 (2024)
Allele T
OR 0.35
p 3.0e-35
N 58,343
Meta-analysisLarge GWAS
European
About RAB31
Enables GDP binding activity; GTP binding activity; and GTPase activity. Involved in several processes, including Golgi to plasma membrane protein transport; cellular response to insulin stimulus; and receptor internalization. Located in early endosome; phagocytic vesicle; and trans-Golgi network membrane. Biomarker of severe acute respiratory syndrome. [provided by Alliance of Genome Resources, Jul 2025]
View all RAB31 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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