C8orf34
chromosome 8 open reading frame 34
Summary
This gene encodes a protein that is related to the cyclic AMP dependent protein kinase regulators. Naturally occurring mutations in this gene are associated with an increased risk for severe toxicities, such as diarrhea and neutropenia, in patients undergoing chemotherapeutic treatment. [provided by RefSeq, Mar 2017]
Known Variants16 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs1218988871 | 8:69,243,304 | C/G | — | uncertain significance |
| rs1517121 | 8:69,258,760 | T/C | intron variant | — |
| rs750929639 | 8:69,358,665 | A/G | — | uncertain significance |
| rs1517114 | 8:69,389,217 | C/G | intron variant | — |
| rs77837731 | 8:69,440,173 | T/C | upstream gene variant | — |
| rs9692812 | 8:69,470,800 | G/A | intron variant | — |
| rs7825271 | 8:69,563,695 | G/A | — | — |
| rs17387279 | 8:69,570,332 | T/G | intron variant | — |
| rs1865442 | 8:69,574,165 | C/T | intron variant | — |
| rs16934882 | 8:69,577,637 | C/A | intron variant | — |
| rs7846438 | 8:69,578,824 | A/G | intron variant | — |
| rs72666766 | 8:69,580,612 | A/G | intron variant | — |
| rs10282983 | 8:69,590,554 | C/T | intron variant | — |
| rs199668114 | 8:69,633,593 | T/C | — | likely benign |
| rs6472419 | 8:69,671,650 | T/A | intron variant | — |
| rs16935110 | 8:69,730,719 | A/T | 3 prime UTR variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.