rs72666766
This is a intron variant variant in the C8orf34 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
Back pain
Freidin MB et al. “Insight into the genetic architecture of back pain and its risk factors from a study of 509,000 individuals.” Pain 160(6):1361-1373 (2019)
Allele A
OR 0.05
p 6.0e-14
N 453,862
Large GWAS
European
About C8orf34
This gene encodes a protein that is related to the cyclic AMP dependent protein kinase regulators. Naturally occurring mutations in this gene are associated with an increased risk for severe toxicities, such as diarrhea and neutropenia, in patients undergoing chemotherapeutic treatment. [provided by RefSeq, Mar 2017]
View all C8orf34 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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