rs77837731
This is a upstream gene variant variant in the C8orf34 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
Moyamoya disease
Jeon JP et al. “Genome-wide association study identifies novel susceptibilities to adult moyamoya disease.” Journal of Human Genetics 68(10):713-720 (2023)
Allele C
OR 7.07
p 2.0e-8
N 512
Small GWAS
East Asian
About C8orf34
This gene encodes a protein that is related to the cyclic AMP dependent protein kinase regulators. Naturally occurring mutations in this gene are associated with an increased risk for severe toxicities, such as diarrhea and neutropenia, in patients undergoing chemotherapeutic treatment. [provided by RefSeq, Mar 2017]
View all C8orf34 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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