rs10802580

GWAS Catalog Trait Associations (3)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

aortic measurement

Benjamins JW et al. Genomic insights in ascending aortic size and distensibility. Ebiomedicine 75:103783 (2022)
Allele A
OR 0.05
p 7.0e-10
N 35,110
Large GWAS

ascending aorta diameter

Pirruccello JP et al. The Genetic Determinants of Aortic Distention. Journal of the American College of Cardiology 81(14):1320-1335 (2023)
Allele A
OR 0.05
p 3.0e-9
N 38,372
Large GWAS
European, NR
Pirruccello JP et al. Deep learning enables genetic analysis of the human thoracic aorta. Nature Genetics 54(1):40-51 (2022)
Allele A
OR 0.05
p 2.0e-8
N 33,637
Large GWAS
European

PR interval

Allele G
OR 0.45
p 7.0e-9
N 292,566
Large GWAS
multi-ancestry

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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