rs10811662
▶GWAS Catalog Trait Associations (13)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (13)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
blood glucose amount
Jee YH et al. “Genome-wide association studies in a large Korean cohort identify quantitative trait loci for 36 traits and illuminate their genetic architectures.” Nature Communications 16(1):4935 (2025)
Allele A
OR 0.07
p 4.0e-98
N 153,950
Large GWAS
East Asian
Chung RH et al. “Multi-omics analysis identifies CpGs near G6PC2 mediating the effects of genetic variants on fasting glucose.” Diabetologia 64(7):1613-1625 (2021)
Allele A
OR 0.07
p 5.0e-11
N 18,122
Large GWAS
East Asian
diabetes mellitus
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 0.13
p 2.0e-75
N 315,668
Major Consortium StudyLarge GWAS
European
diabetic neuropathy
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 0.12
p 7.0e-57
N 434,644
Major Consortium StudyLarge GWAS
European
HbA1c measurement
Kim YJ et al. “The contribution of common and rare genetic variants to variation in metabolic traits in 288,137 East Asians.” Nature Communications 13(1):6642 (2022)
Allele A
OR 0.06
p 2.0e-34
N 288,127
Large GWAS
East Asian
glucose measurement
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele A
OR 0.03
p 2.0e-27
N 394,642
Large GWAS
European
Lagou V et al. “GWAS of random glucose in 476,326 individuals provide insights into diabetes pathophysiology, complications and treatment stratification.” Nature Genetics 55(9):1448-1461 (2023)
Allele A
OR 0.00
p 8.0e-16
N 475,416
Large GWAS
multi-ancestry
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele A
OR 0.05
p 3.0e-15
N 106,371
Major Consortium StudyLarge GWAS
multi-ancestry
diabetic polyneuropathy
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 0.13
p 8.0e-19
N 439,904
Major Consortium StudyLarge GWAS
European
potassium measurement
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 0.03
p 4.0e-15
N 421,503
Major Consortium StudyLarge GWAS
European
diabetes mellitus, family history
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 0.07
p 1.0e-13
N 404,034
Major Consortium StudyLarge GWAS
multi-ancestry
type 2 diabetes mellitus
Bonàs-Guarch S et al. “Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes.” Nature Communications 9(1):321 (2018)
Allele G
OR 1.17
p 1.0e-13
N 70,127
Large GWAS
European
Guindo-Martínez M et al. “The impact of non-additive genetic associations on age-related complex diseases.” Nature Communications 12(1):2436 (2021)
Allele G
OR 0.87
p 4.0e-8
N 56,637
Large GWAS
European
sex hormone-binding globulin measurement
Ruth KS et al. “Using human genetics to understand the disease impacts of testosterone in men and women.” Nature Medicine 26(2):252-258 (2020)
Allele A
OR 0.01
p 1.0e-10
N 368,929
Large GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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