rs10852344
This is a downstream gene variant variant.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
age at menopause
Day FR et al. “Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair.” Nature Genetics 47(11):1294-1303 (2015)
Allele T
OR 0.16
p 1.0e-15
N 69,626
Large GWAS
European
Stolk L et al. “Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways.” Nature Genetics 44(3):260-8 (2012)
Allele T
OR 0.17
p 1.0e-11
N 38,968
Large GWAS
European
Perry JR et al. “A genome-wide association study of early menopause and the combined impact of identified variants.” Human Molecular Genetics 22(7):1465-72 (2013)
Allele T
OR 0.16
p 5.0e-8
N 17,091
Large GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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