Trait
SNPs associated with Age At Menopause
186 genetic variants across 63 genes have been associated with Age At Menopause in published research. Key genes include APCDD1, ARL14EP-DT, AS3MT.
Associated variants186 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs11668344 | TMEM150B | GWAS association (p=0.0e+00) | Large GWAS |
| rs16991615 | MCM8 | GWAS association (p=0.0e+00) | Large GWAS |
| rs353478 | — | GWAS association (p=3.0e-268) | Large GWAS |
| rs3750243 | EIF4EBP1 | GWAS association (p=5.0e-261) | Large GWAS |
| rs12651246 | HELQ | GWAS association (p=6.0e-172) | Large GWAS |
| rs2844466 | PRRC2A | GWAS association (p=1.0e-150) | Large GWAS |
| rs2277339 | PRIM1 | GWAS association (p=2.0e-136) | Large GWAS |
| rs9438982 | — | GWAS association (p=1.0e-118) | Large GWAS |
| rs9348724 | SYCP2L | GWAS association (p=4.0e-112) | Large GWAS |
| rs799903 | BRCA1 | GWAS association (p=2.0e-82) | Large GWAS |
| rs77100210 | — | GWAS association (p=8.0e-79) | Large GWAS |
| rs117146677 | TMEM150B | GWAS association (p=1.0e-76) | Large GWAS |
| rs12898357 | — | GWAS association (p=1.0e-76) | Large GWAS |
| rs9796 | — | GWAS association (p=9.0e-74) | Large GWAS |
| rs28416520 | PIWIL1 | GWAS association (p=2.0e-69) | Large GWAS |
| rs148563363 | MCM8 | GWAS association (p=2.0e-64) | Large GWAS |
| rs138430 | — | GWAS association (p=1.0e-61) | Large GWAS |
| rs274701 | TENT4A | GWAS association (p=3.0e-56) | Large GWAS |
| rs349306 | — | GWAS association (p=1.0e-53) | Large GWAS |
| rs72823382 | SYCP2L | GWAS association (p=9.0e-51) | Large GWAS |
| rs34856659 | — | GWAS association (p=3.0e-49) | Large GWAS |
| rs76928871 | — | GWAS association (p=7.0e-49) | Large GWAS |
| rs10854167 | — | GWAS association (p=1.0e-48) | Large GWAS |
| rs11245450 | — | GWAS association (p=1.0e-47) | Large GWAS |
| rs11670032 | — | GWAS association (p=2.0e-43) | Large GWAS |
| rs62237617 | TTC28 | GWAS association (p=5.0e-42) | Large GWAS |
| rs72755295 | EXO1 | GWAS association (p=1.0e-37) | Large GWAS |
| rs72827480 | — | GWAS association (p=2.0e-34) | Large GWAS |
| rs365132 | UIMC1 | GWAS association (p=1.0e-33) | Large GWAS |
| rs148258173 | FANCB | GWAS association (p=4.0e-33) | Large GWAS |
| rs75770066 | — | GWAS association (p=1.0e-31) | Large GWAS |
| rs7308068 | HELB | GWAS association (p=8.0e-30) | Large GWAS |
| rs45547534 | FANCM | GWAS association (p=2.0e-26) | Large GWAS |
| rs56225015 | — | GWAS association (p=2.0e-24) | Large GWAS |
| rs139906882 | — | GWAS association (p=3.0e-24) | Large GWAS |
| rs10477172 | — | GWAS association (p=3.0e-23) | Large GWAS |
| rs4693089 | HELQ | GWAS association (p=9.0e-23) | Large GWAS |
| rs1889921 | — | GWAS association (p=3.0e-22) | Large GWAS |
| rs2720044 | ASH2L | GWAS association (p=7.0e-22) | Large GWAS |
| rs6810489 | — | GWAS association (p=4.0e-21) | Large GWAS |
| rs4246511 | RHBDL2 | GWAS association (p=5.0e-21) | Large GWAS |
| rs10406053 | — | GWAS association (p=8.0e-21) | Large GWAS |
| rs12046563 | — | GWAS association (p=6.0e-20) | Large GWAS |
| rs140353819 | ZNRF3 | GWAS association (p=6.0e-20) | Large GWAS |
| rs1054875 | — | GWAS association (p=2.0e-19) | Large GWAS |
| rs6899676 | — | GWAS association (p=2.0e-19) | Large GWAS |
| rs12636454 | PPARG | GWAS association (p=2.0e-19) | Large GWAS |
| rs1172822 | BRSK1 | GWAS association (p=2.0e-19) | Large GWAS |
| rs930036 | — | GWAS association (p=3.0e-19) | Large GWAS |
| rs2392836 | — | GWAS association (p=3.0e-19) | Large GWAS |
| rs10804920 | — | GWAS association (p=7.0e-19) | Large GWAS |
| rs4853 | H1-10 | GWAS association (p=2.0e-18) | Large GWAS |
| rs41272475 | SELE | GWAS association (p=9.0e-18) | Large GWAS |
| rs55873183 | — | GWAS association (p=1.0e-17) | Large GWAS |
| rs5030755 | — | GWAS association (p=4.0e-17) | Large GWAS |
| rs1986616 | — | GWAS association (p=4.0e-17) | Large GWAS |
| rs6856693 | — | GWAS association (p=1.0e-16) | Large GWAS |
| rs1046089 | PRRC2A | GWAS association (p=2.0e-16) | Large GWAS |
| rs4886238 | TDRD3 | GWAS association (p=3.0e-16) | Large GWAS |
| rs395962 | — | GWAS association (p=5.0e-16) | Large GWAS |
| rs28474889 | — | GWAS association (p=5.0e-16) | Large GWAS |
| rs12461110 | NLRP11 | GWAS association (p=8.0e-16) | Large GWAS |
| rs7928823 | — | GWAS association (p=1.0e-15) | Large GWAS |
| rs10852344 | — | GWAS association (p=1.0e-15) | Large GWAS |
| rs704795 | — | GWAS association (p=2.0e-15) | Large GWAS |
| rs10049761 | — | GWAS association (p=3.0e-15) | Large GWAS |
| rs569145577 | LINC02076 | GWAS association (p=5.0e-15) | Large GWAS |
| rs707938 | MSH5 | GWAS association (p=7.0e-15) | Large GWAS |
| rs2517388 | ASH2L | GWAS association (p=9.0e-15) | Large GWAS |
| rs10183486 | TLK1 | GWAS association (p=2.0e-14) | Large GWAS |
| rs2236918 | EXO1 | GWAS association (p=8.0e-14) | Large GWAS |
| rs11031006 | ARL14EP-DT | GWAS association (p=9.0e-14) | Large GWAS |
| rs34933909 | ZNF346 | GWAS association (p=9.0e-14) | Large GWAS |
| rs763121 | — | GWAS association (p=2.0e-13) | Large GWAS |
| rs851797 | EXO1 | GWAS association (p=2.0e-13) | Large GWAS |
| rs2547274 | — | GWAS association (p=3.0e-13) | Large GWAS |
| rs6185 | GNRH1 | GWAS association (p=3.0e-13) | Large GWAS |
| rs78566820 | — | GWAS association (p=3.0e-13) | Large GWAS |
| rs2307449 | POLG | GWAS association (p=4.0e-13) | Large GWAS |
| rs9393800 | — | GWAS association (p=4.0e-13) | Large GWAS |
| rs13362006 | — | GWAS association (p=5.0e-13) | Large GWAS |
| rs4972504 | HOXD3 | GWAS association (p=5.0e-13) | Large GWAS |
| rs2303369 | FNDC4 | GWAS association (p=2.0e-12) | Large GWAS |
| rs12211124 | — | GWAS association (p=2.0e-12) | Large GWAS |
| rs660158 | RAD18 | GWAS association (p=2.0e-12) | Large GWAS |
| rs540836853 | — | GWAS association (p=2.0e-12) | Large GWAS |
| rs8176479 | — | GWAS association (p=3.0e-12) | Large GWAS |
| rs76498344 | MCM8 | GWAS association (p=4.0e-12) | Large GWAS |
| rs138114862 | — | GWAS association (p=6.0e-12) | Large GWAS |
| rs2736609 | PMF1 | GWAS association (p=7.0e-12) | Large GWAS |
| rs2153157 | SYCP2L | GWAS association (p=8.0e-12) | Large GWAS |
| rs12294104 | LOC102723403 | GWAS association (p=1.0e-11) | Large GWAS |
| rs2241584 | — | GWAS association (p=2.0e-11) | Large GWAS |
| rs148681796 | — | GWAS association (p=2.0e-11) | Large GWAS |
| rs1800932 | MSH6 | GWAS association (p=3.0e-11) | Large GWAS |
| rs3816424 | PEX5 | GWAS association (p=3.0e-11) | Large GWAS |
| rs12713012 | — | GWAS association (p=3.0e-11) | Large GWAS |
| rs7779 | — | GWAS association (p=3.0e-11) | Large GWAS |
| rs8053204 | MYLK3 | GWAS association (p=4.0e-11) | Large GWAS |
| rs12622788 | — | GWAS association (p=4.0e-11) | Large GWAS |
Showing the top 100 of 186 variants by evidence strength.
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.