rs75770066
▶GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
age at menopause
Day FR et al. “Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair.” Nature Genetics 47(11):1294-1303 (2015)
Allele G
OR 0.85
p 1.0e-31
N 2,545
Large GWAS
European
estradiol measurement
Oppenheimer H et al. “No causal links between estradiol and female's brain and mental health using Mendelian randomization.” Nature Communications 16(1):10915 (2025)
Allele G
OR 1.24
p 7.0e-17
N 207,119
Large GWAS
European
Haas CB et al. “Cross-ancestry Genome-wide Association Studies of Sex Hormone Concentrations in Pre- and Postmenopausal Women.” Endocrinology 163(4) (2022)
Allele G
OR 0.06
p 5.0e-14
N 229,966
Large GWAS
European
chromosome, telomeric region length
Burren OS et al. “Genetic architecture of telomere length in 462,666 UK Biobank whole-genome sequences.” Nature Genetics 56(9):1832-1840 (2024)
Allele A
OR 0.03
p 1.0e-8
N 438,351
Major Consortium StudyLarge GWAS
European
follicle stimulating hormone measurement
Venkatesh SS et al. “Genome-wide analyses identify 25 infertility loci and relationships with reproductive traits across the allele frequency spectrum.” Nature Genetics 57(5):1107-1118 (2025)
Allele G
OR 0.12
p 1.0e-13
N 57,890
Large GWAS
European, South Asian
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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