rs10853087
This variant is located in the GOSR2 gene.
▶GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
blood urea nitrogen amount
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele C
OR 0.03
p 7.0e-36
N 598,949
Major Consortium StudyLarge GWAS
multi-ancestry
hemoglobin measurement
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele G
OR 0.02
p 1.0e-20
N 394,642
Large GWAS
European
high density lipoprotein cholesterol measurement
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele G
OR 0.01
p 2.0e-18
N 394,642
Large GWAS
European
bladder exstrophy
Mingardo E et al. “A genome-wide association study with tissue transcriptomics identifies genetic drivers for classic bladder exstrophy.” Communications Biology 5(1):1203 (2022)
Allele C
OR 1.47
p 1.0e-9
N 7,980
Large GWAS
European
About GOSR2
This gene encodes a trafficking membrane protein which transports proteins among the medial- and trans-Golgi compartments. Due to its chromosomal location and trafficking function, this gene may be involved in familial essential hypertension. [provided by RefSeq, Mar 2016]
View all GOSR2 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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