rs10917477
▶GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
heel bone mineral density
Morris JA et al. “An atlas of genetic influences on osteoporosis in humans and mice.” Nature Genetics 51(2):258-266 (2019)
Allele A
OR 0.02
p 1.0e-17
N 426,824
Large GWAS
European
hypothyroidism
Figuerêdo J et al. “Uncovering the shared genetic components of thyroid disorders and reproductive health.” European Journal of Endocrinology 191(2):211-222 (2024)
Allele G
OR 1.05
p 4.0e-11
N 691,986
Large GWAS
European
Sakaue S et al. “A cross-population atlas of genetic associations for 220 human phenotypes.” Nature Genetics 53(10):1415-1424 (2021)
Allele G
OR 0.06
p 2.0e-10
N 583,911
Large GWAS
multi-ancestry
thyroid carcinoma
White SL et al. “Global multi-ancestry genome-wide analyses identify genes and biological pathways associated with thyroid cancer and benign thyroid diseases.” Nature Genetics 58(2):307-316 (2026)
Allele G
OR 0.07
p 2.0e-10
N 2,917,628
Large GWAS
multi-ancestry
thyroid function
Rawal R et al. “Meta-analysis of two genome-wide association studies identifies four genetic loci associated with thyroid function.” Human Molecular Genetics 21(14):3275-82 (2012)
Allele A
OR 0.06
p 2.0e-8
N 3,736
Meta-analysis
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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