rs10982164

This is a regulatory region variant variant in the ORM2 gene.

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GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

level of serine protease inhibitor Kazal-type 2 in blood

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)

Allele A

OR 0.26

p 8.0e-146

N 47,745

Large GWAS

European

promotilin measurement

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)

Allele A

OR 0.13

p 1.0e-42

N 47,745

Large GWAS

European

About ORM2

This gene encodes a key acute phase plasma protein. Because of its increase due to acute inflammation, this protein is classified as an acute-phase reactant. The specific function of this protein has not yet been determined; however, it may be involved in aspects of immunosuppression. [provided by RefSeq, Jul 2008]

View all ORM2 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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