ORM2

orosomucoid 2

Summary

This gene encodes a key acute phase plasma protein. Because of its increase due to acute inflammation, this protein is classified as an acute-phase reactant. The specific function of this protein has not yet been determined; however, it may be involved in aspects of immunosuppression. [provided by RefSeq, Jul 2008]

Known Variants25 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs3762056	9:117,090,434	C/T	upstream gene variant	—
rs3762055	9:117,090,575	T/C	regulatory region variant	—
rs10982164	9:117,091,067	G/A	regulatory region variant	—
rs7040440	9:117,091,074	C/T	regulatory region variant	—
rs142414765	9:117,092,020	G/C	—	—
rs768724177	9:117,092,189	C/T	—	uncertain significance
rs143336597	9:117,092,203	C/T	—	likely benign
rs774274413	9:117,092,233	G/A	—	uncertain significance
rs755873204	9:117,092,263	G/C	—	uncertain significance
rs748201206	9:117,092,284	G/A	—	uncertain significance
rs370008862	9:117,092,296	C/T	—	likely benign
rs201562247	9:117,092,756	G/A	—	uncertain significance
rs2490488105	9:117,092,786	C/G	—	uncertain significance
rs149310648	9:117,093,115	C/T	—	uncertain significance
rs760081372	9:117,093,902	G/C	—	likely benign
rs78377107	9:117,093,923	C/T	—	likely benign
rs142563384	9:117,094,149	C/T	—	benign
rs148221879	9:117,094,159	G/C	—	uncertain significance
rs1214997559	9:117,094,162	T/G	—	uncertain significance
rs149574658	9:117,094,207	A/C	—	uncertain significance
rs113229705	9:117,094,854	C/T	downstream gene variant	—
rs1687417	9:117,095,146	T/G	downstream gene variant	—
rs1829888432	9:117,095,373	C/A	—	uncertain significance
rs565103849	9:117,095,379	G/A	—	uncertain significance
rs2490500090	9:117,095,404	G/A	—	likely benign

Gene information from NCBI Gene. Variant classifications from ClinVar.