rs1687417

This is a downstream gene variant variant in the ORM2 gene.

GWAS Catalog Trait Associations (4)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

level of alpha-1-acid glycoprotein 1 in blood

Allele G
OR 0.21
p 9.0e-286
N 47,745
Large GWAS
European

gdnf family receptor alpha-1 measurement

Allele G
OR 0.05
p 1.0e-21
N 47,745
Large GWAS
European

coagulation factor X amount

Allele G
OR 0.05
p 3.0e-18
N 47,745
Large GWAS
European

vitamin k-dependent protein S measurement

Allele G
OR 0.05
p 2.0e-16
N 47,745
Large GWAS
European

About ORM2

This gene encodes a key acute phase plasma protein. Because of its increase due to acute inflammation, this protein is classified as an acute-phase reactant. The specific function of this protein has not yet been determined; however, it may be involved in aspects of immunosuppression. [provided by RefSeq, Jul 2008]

View all ORM2 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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