rs3762056

This is a upstream gene variant variant in the ORM2 gene.

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GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

coagulation factor X amount

Sun BB et al. “Genomic atlas of the human plasma proteome.” Nature 558(7708):73-79 (2018)

Allele T

OR —

β 0.590

p 3.0e-34

N 3,301

Large GWAS

European

coagulation factor XA measurement

Sun BB et al. “Genomic atlas of the human plasma proteome.” Nature 558(7708):73-79 (2018)

Allele T

OR —

β 0.570

p 5.0e-32

N 3,301

Large GWAS

European

About ORM2

This gene encodes a key acute phase plasma protein. Because of its increase due to acute inflammation, this protein is classified as an acute-phase reactant. The specific function of this protein has not yet been determined; however, it may be involved in aspects of immunosuppression. [provided by RefSeq, Jul 2008]

View all ORM2 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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