rs1104608

▶

GWAS Catalog Trait Associations (5)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

alcohol consumption quality

Evangelou E et al. “New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders.” Nature Human Behaviour 3(9):950-961 (2019)
Allele C
OR 0.01
p 1.0e-14
N 480,842
Large GWAS
European
Liu M et al. “Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.” Nature Genetics 51(2):237-244 (2019)
Allele C
OR 0.01
p 3.0e-12
N 1,039,210
Large GWAS
European
Zhou H et al. “Genome-wide meta-analysis of problematic alcohol use in 435,563 individuals yields insights into biology and relationships with other traits.” Nature Neuroscience 23(7):809-818 (2020)
Allele C
OR 0.01
p 4.0e-12
N 972,915
Meta-analysisLarge GWAS
European
Brazel DM et al. “Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use.” Biological Psychiatry 85(11):946-955 (2019)
Allele C
OR 0.02
p 2.0e-10
N 357,854
Meta-analysisLarge GWAS
European

carbohydrate intake measurement

Merino J et al. “Genetic analysis of dietary intake identifies new loci and functional links with metabolic traits.” Nature Human Behaviour 6(1):155-163 (2022)
Allele C
OR 0.16
p 2.0e-11
N 282,271
Large GWAS
European

testosterone measurement

Ruth KS et al. “Using human genetics to understand the disease impacts of testosterone in men and women.” Nature Medicine 26(2):252-258 (2020)
Allele C
OR 0.01
p 6.0e-9
N 382,988
Large GWAS
European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

Community Wiki

No community notes yet for this variant. Sign in to start one.

Comments

Sign in to join the discussion.

Loading comments…