rs11127048

This is a intergenic variant variant.

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GWAS Catalog Trait Associations (23)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

triglyceride measurement

Kim YJ et al. “The contribution of common and rare genetic variants to variation in metabolic traits in 288,137 East Asians.” Nature Communications 13(1):6642 (2022)
Allele A
OR 0.10
p 8.0e-232
N 288,127
Large GWAS
East Asian

alcohol consumption quality

Saunders GRB et al. “Genetic diversity fuels gene discovery for tobacco and alcohol use.” Nature 612(7941):720-724 (2022)
Allele A
OR 0.02
p 1.0e-127
N 2,428,851
Large GWAS
European
Clarke TK et al. “Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112 117).” Molecular Psychiatry 22(10):1376-1384 (2017)
Allele A
OR 0.04
p 1.0e-16
N 112,117
Major Consortium StudyLarge GWAS
European

total cholesterol measurement

Kim YJ et al. “The contribution of common and rare genetic variants to variation in metabolic traits in 288,137 East Asians.” Nature Communications 13(1):6642 (2022)
Allele A
OR 0.05
p 2.0e-58
N 288,127
Large GWAS
East Asian

oxytocin-neurophysin 1 measurement

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele A
OR 0.05
p 4.0e-23
N 47,745
Large GWAS
European

apolipoprotein B measurement

Richardson TG et al. “Characterising metabolomic signatures of lipid-modifying therapies through drug target mendelian randomisation.” Plos Biology 20(2):e3001547 (2022)
Allele G
OR 0.04
p 3.0e-21
N 115,082
Large GWAS
European

remnant cholesterol measurement

Richardson TG et al. “Characterising metabolomic signatures of lipid-modifying therapies through drug target mendelian randomisation.” Plos Biology 20(2):e3001547 (2022)
Allele G
OR 0.04
p 9.0e-20
N 115,082
Large GWAS
European

vitamin D level

Manousaki D et al. “Genome-wide Association Study for Vitamin D Levels Reveals 69 Independent Loci.” American Journal of Human Genetics 106(3):327-337 (2020)
Allele A
OR 0.02
p 6.0e-19
N 443,734
Large GWAS
European

coffee consumption measurement

Said MA et al. “Associations of Observational and Genetically Determined Caffeine Intake With Coronary Artery Disease and Diabetes Mellitus.” Journal of the American Heart Association 9(24):e016808 (2020)
Allele G
OR 0.02
p 8.0e-17
N 373,522
Large GWAS
European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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