rs11156429

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GWAS Catalog Trait Associations (4)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

major depressive disorder

Meng X et al. “Multi-ancestry genome-wide association study of major depression aids locus discovery, fine mapping, gene prioritization and causal inference.” Nature Genetics 56(2):222-233 (2024)

Allele T

OR 0.02

p 5.0e-12

N 1,820,689

Large GWAS

multi-ancestry

testosterone measurement

Fantus RJ et al. “Genetic Susceptibility for Low Testosterone in Men and Its Implications in Biology and Screening: Data from the UK Biobank.” European Urology Open Science 29:36-46 (2021)

Allele T

OR 1.08

p 1.0e-11

N 111,676

Major Consortium StudyLarge GWAS

European

BMI-adjusted waist circumference

Graff M et al. “Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.” Plos Genetics 13(4):e1006528 (2017)

Allele T

OR 0.03

p 1.0e-10

N 122,328

Meta-analysisLarge GWAS

multi-ancestry

puberty onset measurement

Hollis B et al. “Genomic analysis of male puberty timing highlights shared genetic basis with hair colour and lifespan.” Nature Communications 11(1):1536 (2020)

Allele T

OR 0.01

p 1.0e-20

N 187,241

Large GWAS

European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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