Trait
SNPs associated with Major depressive disorder
800 genetic variants across 173 genes have been associated with Major depressive disorder in published research. Key genes include ABT1, AGBL4, ANO10.
Associated variants800 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs2568958 | LOC105378797 | GWAS association (p=4.0e-52) | Meta-analysis |
| rs30266 | LOC105379109 | GWAS association (p=2.0e-45) | Meta-analysis |
| rs1568452 | — | GWAS association (p=3.0e-40) | Meta-analysis |
| rs61902811 | — | GWAS association (p=4.0e-39) | Meta-analysis |
| rs1095626 | RSRC1 | GWAS association (p=6.0e-39) | Meta-analysis |
| rs200949 | H1-5 | GWAS association (p=2.0e-37) | Meta-analysis |
| rs5995992 | — | GWAS association (p=3.0e-35) | Meta-analysis |
| rs10890020 | — | GWAS association (p=3.0e-34) | Meta-analysis |
| rs61990288 | LRFN5 | GWAS association (p=2.0e-31) | Meta-analysis |
| rs301799 | RERE | GWAS association (p=4.0e-31) | Meta-analysis |
| rs11135349 | — | GWAS association (p=2.0e-30) | Meta-analysis |
| rs7030813 | PAX5 | GWAS association (p=9.0e-30) | Meta-analysis |
| rs9592461 | — | GWAS association (p=1.0e-28) | Meta-analysis |
| rs7227069 | DCC | GWAS association (p=2.0e-28) | Meta-analysis |
| rs7200826 | — | GWAS association (p=3.0e-28) | Meta-analysis |
| rs12967143 | — | GWAS association (p=2.0e-27) | Meta-analysis |
| rs3823624 | — | GWAS association (p=2.0e-26) | Meta-analysis |
| rs1021363 | — | GWAS association (p=2.0e-25) | Meta-analysis |
| rs1343605 | — | GWAS association (p=2.0e-25) | Meta-analysis |
| rs7932640 | — | GWAS association (p=3.0e-25) | Meta-analysis |
| rs1045430 | — | GWAS association (p=4.0e-25) | Meta-analysis |
| rs12923444 | — | GWAS association (p=2.0e-24) | Meta-analysis |
| rs77087420 | KIAA1109 | GWAS association (p=3.0e-24) | Meta-analysis |
| rs2043539 | TMEM106B | GWAS association (p=8.0e-24) | Meta-analysis |
| rs7198928 | — | GWAS association (p=4.0e-23) | Meta-analysis |
| rs12052908 | — | GWAS association (p=4.0e-22) | Meta-analysis |
| rs10061069 | — | GWAS association (p=5.0e-22) | Meta-analysis |
| rs7807677 | — | GWAS association (p=5.0e-22) | Meta-analysis |
| rs3793577 | — | GWAS association (p=6.0e-22) | Meta-analysis |
| rs10149470 | LOC124903392 | GWAS association (p=7.0e-22) | Meta-analysis |
| rs913930 | TLR4 | GWAS association (p=1.0e-21) | Meta-analysis |
| rs3099439 | — | GWAS association (p=2.0e-21) | Meta-analysis |
| rs113188507 | — | GWAS association (p=3.0e-21) | Meta-analysis |
| rs60157091 | — | GWAS association (p=6.0e-21) | Meta-analysis |
| rs45510091 | — | GWAS association (p=8.0e-21) | Meta-analysis |
| rs4772087 | — | GWAS association (p=2.0e-20) | Meta-analysis |
| rs10913112 | — | GWAS association (p=2.0e-20) | Meta-analysis |
| rs3213572 | — | GWAS association (p=6.0e-20) | Meta-analysis |
| rs17641524 | — | GWAS association (p=8.0e-20) | Meta-analysis |
| rs12967855 | CELF4 | GWAS association (p=1.0e-19) | Meta-analysis |
| rs1933802 | — | GWAS association (p=1.0e-19) | Meta-analysis |
| rs7193263 | — | GWAS association (p=4.0e-19) | Meta-analysis |
| rs1002656 | — | GWAS association (p=5.0e-19) | Meta-analysis |
| rs12552 | OLFM4 | GWAS association (p=6.0e-19) | Meta-analysis |
| rs1890946 | — | GWAS association (p=9.0e-19) | Meta-analysis |
| rs8037355 | — | GWAS association (p=2.0e-18) | Meta-analysis |
| rs1226412 | — | GWAS association (p=3.0e-18) | Meta-analysis |
| rs58104186 | — | GWAS association (p=4.0e-18) | Meta-analysis |
| rs143186028 | EMILIN3 | GWAS association (p=7.0e-18) | Meta-analysis |
| rs11579246 | ELAVL4 | GWAS association (p=9.0e-18) | Meta-analysis |
| rs13084037 | KLHDC8B | GWAS association (p=2.0e-17) | Meta-analysis |
| rs2876520 | — | GWAS association (p=3.0e-17) | Meta-analysis |
| rs2029865 | — | GWAS association (p=4.0e-17) | Meta-analysis |
| rs1354115 | — | GWAS association (p=4.0e-17) | Meta-analysis |
| rs56314503 | LOC107984536 | GWAS association (p=1.0e-16) | Meta-analysis |
| rs34653192 | — | GWAS association (p=3.0e-16) | Meta-analysis |
| rs2149351 | — | GWAS association (p=4.0e-16) | Meta-analysis |
| rs2509805 | — | GWAS association (p=5.0e-16) | Meta-analysis |
| rs263645 | — | GWAS association (p=7.0e-16) | Meta-analysis |
| rs141954845 | FHIT | GWAS association (p=1.0e-15) | Meta-analysis |
| rs1982277 | — | GWAS association (p=1.0e-15) | Meta-analysis |
| rs1448938 | — | GWAS association (p=4.0e-15) | Meta-analysis |
| rs7685686 | HTT | GWAS association (p=6.0e-15) | Meta-analysis |
| rs62091461 | RAB27B | GWAS association (p=2.0e-14) | Meta-analysis |
| rs12624433 | — | GWAS association (p=2.0e-14) | Meta-analysis |
| rs8099160 | — | GWAS association (p=2.0e-14) | Meta-analysis |
| rs4801157 | — | GWAS association (p=3.0e-14) | Meta-analysis |
| rs7117514 | SHANK2 | GWAS association (p=4.0e-14) | Meta-analysis |
| rs198457 | — | GWAS association (p=5.0e-14) | Meta-analysis |
| rs7758630 | — | GWAS association (p=8.0e-14) | Meta-analysis |
| rs2247523 | — | GWAS association (p=9.0e-14) | Meta-analysis |
| rs6783233 | — | GWAS association (p=1.0e-13) | Meta-analysis |
| rs7837935 | CYP7B1 | GWAS association (p=1.0e-13) | Meta-analysis |
| rs7241572 | KCNG2 | GWAS association (p=3.0e-13) | Meta-analysis |
| rs75581564 | — | GWAS association (p=3.0e-13) | Meta-analysis |
| rs34488670 | SEMA6D | GWAS association (p=5.0e-13) | Meta-analysis |
| rs7585722 | — | GWAS association (p=5.0e-13) | Meta-analysis |
| rs62188629 | — | GWAS association (p=5.0e-13) | Meta-analysis |
| rs34937911 | — | GWAS association (p=5.0e-13) | Meta-analysis |
| rs997934 | — | GWAS association (p=5.0e-13) | Meta-analysis |
| rs56887639 | — | GWAS association (p=6.0e-13) | Meta-analysis |
| rs10817969 | ASTN2 | GWAS association (p=1.0e-12) | Meta-analysis |
| rs2670139 | — | GWAS association (p=2.0e-12) | Meta-analysis |
| rs12968428 | — | GWAS association (p=2.0e-12) | Meta-analysis |
| rs9363467 | — | GWAS association (p=3.0e-12) | Meta-analysis |
| rs1431181 | — | GWAS association (p=3.0e-12) | Meta-analysis |
| rs1152578 | ESR2 | GWAS association (p=4.0e-12) | Meta-analysis |
| rs4346585 | — | GWAS association (p=5.0e-12) | Meta-analysis |
| rs1956373 | — | GWAS association (p=6.0e-12) | Meta-analysis |
| rs78337797 | — | GWAS association (p=1.0e-11) | Meta-analysis |
| rs16887442 | — | GWAS association (p=1.0e-11) | Meta-analysis |
| rs4277413 | — | GWAS association (p=1.0e-11) | Meta-analysis |
| rs169235 | CACNA1E | GWAS association (p=2.0e-11) | Meta-analysis |
| rs8089865 | — | GWAS association (p=3.0e-11) | Meta-analysis |
| rs12966052 | LINC03035 | GWAS association (p=4.0e-11) | Meta-analysis |
| rs2956287 | — | GWAS association (p=5.0e-11) | Meta-analysis |
| rs3823612 | TMEM106B | GWAS association (p=5.0e-11) | Meta-analysis |
| rs1409379 | — | GWAS association (p=8.0e-11) | Meta-analysis |
| rs57344483 | — | GWAS association (p=1.0e-10) | Meta-analysis |
| rs72710803 | — | GWAS association (p=1.0e-10) | Meta-analysis |
Showing the top 100 of 800 variants by evidence strength.
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.