ABT1
activator of basal transcription 1
Summary
Basal transcription of genes by RNA polymerase II requires the interaction of TATA-binding protein (TBP) with the core region of class II promoters. Studies in mouse suggest that the protein encoded by this gene likely activates basal transcription from class II promoters by interaction with TBP and the class II promoter DNA. [provided by RefSeq, Jul 2008]
Known Variants21 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs2533531189 | 6:26,597,272 | A/G | — | uncertain significance |
| rs367775660 | 6:26,597,274 | A/T | — | uncertain significance |
| rs371015299 | 6:26,597,284 | C/T | — | uncertain significance |
| rs782027697 | 6:26,597,334 | C/T | — | uncertain significance |
| rs782731559 | 6:26,597,361 | G/A | — | uncertain significance |
| rs781793691 | 6:26,597,383 | G/A | — | uncertain significance |
| rs377045670 | 6:26,597,393 | C/A | — | uncertain significance |
| rs144740190 | 6:26,598,145 | G/A | — | uncertain significance |
| rs1764924695 | 6:26,598,186 | G/A | — | uncertain significance |
| rs782010945 | 6:26,598,259 | G/C | — | uncertain significance |
| rs782460604 | 6:26,598,282 | A/G | — | uncertain significance |
| rs1554144775 | 6:26,598,515 | C/G | — | uncertain significance |
| rs1764932177 | 6:26,598,601 | G/A | — | uncertain significance |
| rs199547663 | 6:26,598,608 | A/G | — | uncertain significance |
| rs568927550 | 6:26,598,631 | C/A | — | uncertain significance |
| rs151288548 | 6:26,598,649 | G/A | — | uncertain significance |
| rs140562891 | 6:26,598,664 | C/T | — | uncertain significance |
| rs367868700 | 6:26,598,677 | C/G | — | uncertain significance |
| rs782187306 | 6:26,598,784 | C/T | — | uncertain significance |
| rs1230482183 | 6:26,598,850 | C/T | — | uncertain significance |
| rs45527431 | 6:26,599,509 | A/G | 3 prime UTR variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.