rs30266

This variant is located in the LOC105379109 gene.

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GWAS Catalog Trait Associations (4)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

major depressive disorder

Howard DM et al. “Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions.” Nature Neuroscience 22(3):343-352 (2019)
Allele A
OR 1.03
p 2.0e-45
N 807,553
Meta-analysisLarge GWAS
European
Yao X et al. “Integrative analysis of genome-wide association studies identifies novel loci associated with neuropsychiatric disorders.” Translational Psychiatry 11(1):69 (2021)
Allele A
OR 0.04
p 7.0e-19
N 500,199
Large GWAS
European
Cai N et al. “Minimal phenotyping yields genome-wide association signals of low specificity for major depression.” Nature Genetics 52(4):437-447 (2020)
Allele A
OR 1.04
p 4.0e-12
N 332,622
Large GWAS
European

attention deficit hyperactivity disorder

van der Laan CM et al. “Genome-wide association meta-analysis of childhood ADHD symptoms and diagnosis identifies new loci and potential effector genes.” Nature Genetics 57(10):2427-2435 (2025)
Allele A
OR 0.02
p 6.0e-15
N 299,017
Meta-analysisLarge GWAS
European

loneliness measurement

Day FR et al. “Elucidating the genetic basis of social interaction and isolation.” Nature Communications 9(1):2457 (2018)
Allele G
OR 0.01
p 8.0e-9
N 445,024
Large GWAS
European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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