rs7193263
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
major depressive disorder
Howard DM et al. “Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions.” Nature Neuroscience 22(3):343-352 (2019)
Allele G
OR 1.02
p 4.0e-19
N 807,553
Meta-analysisLarge GWAS
European
Meng X et al. “Multi-ancestry genome-wide association study of major depression aids locus discovery, fine mapping, gene prioritization and causal inference.” Nature Genetics 56(2):222-233 (2024)
Allele G
OR 0.02
p 1.0e-12
N 1,820,689
Large GWAS
multi-ancestry
Als TD et al. “Depression pathophysiology, risk prediction of recurrence and comorbid psychiatric disorders using genome-wide analyses.” Nature Medicine 29(7):1832-1844 (2023)
Allele G
OR 0.02
p 6.0e-11
N 1,349,887
Large GWAS
European
Nagel M et al. “Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.” Nature Genetics 50(7):920-927 (2018)
Allele G
OR 6.48
p 9.0e-11
N 688,809
Meta-analysisLarge GWAS
European
depressive symptom measurement
Turley P et al. “Multi-trait analysis of genome-wide association summary statistics using MTAG.” Nature Genetics 50(2):229-237 (2018)
Allele G
OR 0.02
p 4.0e-11
N 354,862
Large GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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