rs11170516

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GWAS Catalog Trait Associations (4)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

mean corpuscular hemoglobin

Sakaue S et al. “A cross-population atlas of genetic associations for 220 human phenotypes.” Nature Genetics 53(10):1415-1424 (2021)

Allele A

OR 0.03

p 4.0e-39

N 478,500

Large GWAS

multi-ancestry

high density lipoprotein cholesterol measurement

Richardson TG et al. “Evaluating the relationship between circulating lipoprotein lipids and apolipoproteins with risk of coronary heart disease: A multivariable Mendelian randomisation analysis.” Plos Medicine 17(3):e1003062 (2020)

Allele G

OR 0.02

p 2.0e-12

N 403,943

Large GWAS

European

erythrocyte count

Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)

Allele G

OR 0.02

p 2.0e-11

N 581,830

Major Consortium StudyLarge GWAS

multi-ancestry

hypospadias

Chen Z et al. “Genome-wide association study in Chinese cohort identifies one novel hypospadias risk associated locus at 12q13.13.” Bmc Medical Genomics 12(1):196 (2019)

Allele G

OR 1.96

p 4.0e-9

N 1,130

Large GWAS

East Asian

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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