rs113021516

This is a upstream gene variant variant in the MSL2 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

sleep duration trait

Scammell BH et al. “Multi-ancestry genome-wide analysis identifies shared genetic effects and common genetic variants for self-reported sleep duration.” Human Molecular Genetics 32(18):2797-2807 (2023)

Allele G

OR 0.02

p 6.0e-12

N 483,235

Large GWAS

multi-ancestry

About MSL2

Enables histone H2B ubiquitin ligase activity. Involved in DNA damage response and protein monoubiquitination. Located in nucleus. Part of MSL complex. Is active in chromatin. [provided by Alliance of Genome Resources, Jul 2025]

View all MSL2 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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