rs1134956
This variant is located in the CFAP69 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
pulse pressure measurement
Surendran P et al. “Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals.” Nature Genetics 52(12):1314-1332 (2020)
Allele T
OR 0.12
p 4.0e-11
N 810,865
Meta-analysisLarge GWAS
European
▶ClinVar annotation
Benign★★★☆
3 submitters1 publicationSpermatogenic failure 24; not provided; CFAP69-related disorder
View on ClinVar →About CFAP69
Acts upstream of or within sperm axoneme assembly. Located in cytoplasm and sperm midpiece. Implicated in spermatogenic failure 24. [provided by Alliance of Genome Resources, Jul 2025]
View all CFAP69 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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