rs113927489
This is a intergenic variant variant in the FAM163B gene.
▶GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
smoking cessation
Saunders GRB et al. “Genetic diversity fuels gene discovery for tobacco and alcohol use.” Nature 612(7941):720-724 (2022)
Allele G
OR 0.04
p 6.0e-76
N 1,400,535
Large GWAS
European, East Asian, Hispanic or Latin American, African unspecified
cigarettes per day measurement
Saunders GRB et al. “Genetic diversity fuels gene discovery for tobacco and alcohol use.” Nature 612(7941):720-724 (2022)
Allele G
OR 0.05
p 7.0e-64
N 783,784
Large GWAS
European, East Asian, Hispanic or Latin American, African unspecified
chronic obstructive pulmonary disease
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele C
OR 0.07
p 1.0e-19
N 418,504
Major Consortium StudyLarge GWAS
European
smoking initiation
Saunders GRB et al. “Genetic diversity fuels gene discovery for tobacco and alcohol use.” Nature 612(7941):720-724 (2022)
Allele G
OR 0.01
p 6.0e-16
N 3,382,012
Large GWAS
European, East Asian, Hispanic or Latin American, African unspecified
About FAM163B
Predicted to be located in membrane. [provided by Alliance of Genome Resources, Jul 2025]
View all FAM163B variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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