rs114138180

This is a upstream gene variant variant in the EVI5 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

low density lipoprotein cholesterol measurement

Graham SE et al. “The power of genetic diversity in genome-wide association studies of lipids.” Nature 600(7890):675-679 (2021)

Allele T

OR 0.10

p 6.0e-25

N 99,432

Large GWAS

African American or Afro-Caribbean, African unspecified

About EVI5

Enables GTPase activator activity and small GTPase binding activity. Involved in positive regulation of GTPase activity and retrograde transport, endosome to Golgi. Located in cytosol. [provided by Alliance of Genome Resources, Jul 2025]

View all EVI5 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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