rs114908185
This is a synonymous variant in the MUC22 gene — it does not change the protein's amino acid sequence.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
Stevens-Johnson syndrome, toxic epidermal necrolysis, response to methazolamide
Jiang M et al. “Unique motif shared by HLA-B*59:01 and HLA-B*55:02 is associated with methazolamide-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in Han Chinese.” Journal of the European Academy of Dermatology and Venereology : Jeadv 36(6):873-880 (2022)
Allele A
OR 31.12
p 7.0e-9
N 821
Small GWAS
East Asian
About MUC22
Predicted to be located in membrane. [provided by Alliance of Genome Resources, Jul 2025]
View all MUC22 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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