Trait
SNPs associated with Stevens-Johnson syndrome, toxic epidermal necrolysis, response to methazolamide
8 genetic variants across 6 genes have been associated with Stevens-Johnson syndrome, toxic epidermal necrolysis, response to methazolamide in published research. Key genes include BAG6, HLA-C, MSH5.
Associated variants8 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs1131151 | HLA-C | GWAS association (p=4.0e-12) | Small GWAS |
| rs2074494 | HLA-C | GWAS association (p=5.0e-12) | Small GWAS |
| rs11509487 | — | GWAS association (p=1.0e-09) | Small GWAS |
| rs28381346 | MSH5 | GWAS association (p=5.0e-09) | Small GWAS |
| rs114908185 | MUC22 | GWAS association (p=7.0e-09) | Small GWAS |
| rs150289893 | SLC35B3 | GWAS association (p=2.0e-08) | Small GWAS |
| rs55765602 | TAP2 | GWAS association (p=3.0e-08) | Small GWAS |
| rs116953913 | BAG6 | GWAS association (p=5.0e-08) | Small GWAS |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.