rs115400054

This is a intron variant variant in the ICA1L gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

total cholesterol measurement

Surakka I et al. “The impact of low-frequency and rare variants on lipid levels.” Nature Genetics 47(6):589-97 (2015)

Allele C

OR 0.05

p 5.0e-9

N 62,166

Large GWAS

European

About ICA1L

Predicted to enable protein domain specific binding activity. Predicted to be involved in regulation of transport. Predicted to act upstream of or within spermatid development. Predicted to be located in acrosomal vesicle. Predicted to be active in Golgi apparatus. [provided by Alliance of Genome Resources, Jul 2025]

View all ICA1L variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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