rs11592748
This variant is located in the BICC1 gene.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
glomerular filtration rate
Robinson-Cohen C et al. “Genome-Wide Association Study of CKD Progression.” Journal of the American Society of Nephrology : Jasn 34(9):1547-1559 (2023)
Allele A
OR 0.13
p 6.0e-9
N 116,960
Large GWAS
multi-ancestry
gout
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele A
OR 0.13
p 3.0e-13
N 443,173
Major Consortium StudyLarge GWAS
European
About BICC1
This gene encodes an RNA-binding protein that is active in regulating gene expression by modulating protein translation during embryonic development. Mouse studies identified the corresponding protein to be under strict control during cell differentiation and to be a maternally provided gene product. [provided by RefSeq, Apr 2009]
View all BICC1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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