rs1159619
This variant is located in the CENPW gene.
▶GWAS Catalog Trait Associations (5)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (5)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
glutamine measurement
Zoodsma M et al. “A genetic map of human metabolism across the allele frequency spectrum.” Nature Genetics 57(10):2445-2455 (2025)
Allele A
OR 0.03
p 2.0e-63
N 450,015
Large GWAS
multi-ancestry
low density lipoprotein cholesterol measurement
Koskeridis F et al. “Pleiotropic genetic architecture and novel loci for C-reactive protein levels.” Nature Communications 13(1):6939 (2022)
Allele A
OR 0.01
p 1.0e-14
N 361,194
Large GWAS
European
triglyceride measurement
Koskeridis F et al. “Pleiotropic genetic architecture and novel loci for C-reactive protein levels.” Nature Communications 13(1):6939 (2022)
Allele A
OR 0.02
p 7.0e-11
N 361,194
Large GWAS
European
abdominal adipose tissue measurement
Agrawal S et al. “Inherited basis of visceral, abdominal subcutaneous and gluteofemoral fat depots.” Nature Communications 13(1):3771 (2022)
Allele C
OR 0.05
p 1.0e-10
N 37,641
Large GWAS
European, East Asian, South Asian, African unspecified, NR
feeling nervous measurement
Nagel M et al. “Item-level analyses reveal genetic heterogeneity in neuroticism.” Nature Communications 9(1):905 (2018)
Allele A
OR 5.69
p 1.0e-8
N 373,121
Large GWAS
European
About CENPW
Predicted to enable DNA binding activity and protein heterodimerization activity. Involved in chromosome segregation; kinetochore assembly; and mitotic cell cycle. Located in kinetochore and nucleoplasm. Part of inner kinetochore. [provided by Alliance of Genome Resources, Jul 2025]
View all CENPW variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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