rs11599236
▶GWAS Catalog Trait Associations (8)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (8)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
wellbeing measurement
Baselmans BML et al. “Multivariate genome-wide analyses of the well-being spectrum.” Nature Genetics 51(3):445-451 (2019)
Allele C
OR 0.01
p 1.0e-15
N 2,083,151
Large GWAS
European
self reported educational attainment
Lee JJ et al. “Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.” Nature Genetics 50(8):1112-1121 (2018)
Allele T
OR 0.01
p 1.0e-13
N 1,131,881
Large GWAS
European
feeling miserable measurement
Nagel M et al. “Item-level analyses reveal genetic heterogeneity in neuroticism.” Nature Communications 9(1):905 (2018)
Allele T
OR 7.05
p 2.0e-12
N 376,097
Large GWAS
European
mood disorder, major depressive disorder
Nagel M et al. “Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.” Nature Genetics 50(7):920-927 (2018)
Allele C
OR 0.02
p 3.0e-11
N 357,957
Meta-analysisLarge GWAS
European
attention deficit hyperactivity disorder, bipolar disorder, autism spectrum disorder, schizophrenia, major depressive disorder
Yao X et al. “Integrative analysis of genome-wide association studies identifies novel loci associated with neuropsychiatric disorders.” Translational Psychiatry 11(1):69 (2021)
Allele T
OR 6.18
p 6.0e-10
N 728,648
Large GWAS
European
total cholesterol measurement, peripheral arterial disease
Bellomo TR et al. “Multi-Trait Genome-Wide Association Study of Atherosclerosis Detects Novel Pleiotropic Loci.” Frontiers in Genetics 12:787545 (2021)
Allele T
OR —
p 2.0e-8
N 747,009
Large GWAS
European
major depressive disorder
Cai N et al. “Minimal phenotyping yields genome-wide association signals of low specificity for major depression.” Nature Genetics 52(4):437-447 (2020)
Allele T
OR 1.03
p 3.0e-8
N 332,622
Large GWAS
European
multisite chronic pain
Johnston KJA et al. “Genome-wide association study of multisite chronic pain in UK Biobank.” Plos Genetics 15(6):e1008164 (2019)
Allele T
OR 0.01
p 3.0e-8
N 387,649
Major Consortium StudyLarge GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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