rs11603023

This is a regulatory region variant variant in the PHLDB1 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

total cholesterol measurement

Willer CJ et al. “Discovery and refinement of loci associated with lipid levels.” Nature Genetics 45(11):1274-1283 (2013)

Allele T

OR —

β 0.022

p 1.0e-8

N 94,595

Large GWAS

European

About PHLDB1

Involved in regulation of embryonic development; regulation of epithelial to mesenchymal transition; and regulation of microtubule cytoskeleton organization. Located in basal cortex. Implicated in osteogenesis imperfecta. [provided by Alliance of Genome Resources, Apr 2025]

View all PHLDB1 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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