rs116362708

This is a intron variant variant in the SLC44A5 gene.

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GWAS Catalog Trait Associations (3)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

depressive symptom measurement

Baselmans BML et al. “Multivariate genome-wide analyses of the well-being spectrum.” Nature Genetics 51(3):445-451 (2019)

Allele A

OR 0.01

p 3.0e-8

N 1,067,913

Large GWAS

European

neuroticism measurement

Baselmans BML et al. “Multivariate genome-wide analyses of the well-being spectrum.” Nature Genetics 51(3):445-451 (2019)

Allele A

OR 0.02

p 3.0e-8

N 523,783

Large GWAS

European

mood disorder, major depressive disorder

Nagel M et al. “Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.” Nature Genetics 50(7):920-927 (2018)

Allele A

OR 0.03

p 4.0e-8

N 357,957

Meta-analysisLarge GWAS

European

About SLC44A5

Enables choline transmembrane transporter activity. Involved in choline transport. Located in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]

View all SLC44A5 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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