Trait
SNPs associated with Neuroticism
1169 genetic variants across 148 genes have been associated with Neuroticism in published research. Key genes include ACVR1B, AQR, AREL1.
Associated variants1,169 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs2921036 | — | GWAS association (p=3.0e-32) | Meta-analysis |
| rs77804065 | LINC02210-CRHR1 | GWAS association (p=1.0e-31) | Meta-analysis |
| rs199447 | NSF | GWAS association (p=2.0e-26) | Meta-analysis |
| rs11082011 | CELF4 | GWAS association (p=3.0e-23) | Meta-analysis |
| rs4799461 | — | GWAS association (p=1.0e-21) | Meta-analysis |
| rs1560312 | MAPT | GWAS association (p=5.0e-21) | Meta-analysis |
| rs8067056 | — | GWAS association (p=1.0e-20) | Meta-analysis |
| rs1544905 | LOC107985118 | GWAS association (p=6.0e-19) | Meta-analysis |
| rs9611519 | L3MBTL2 | GWAS association (p=1.0e-18) | Meta-analysis |
| rs7111031 | — | GWAS association (p=2.0e-18) | Meta-analysis |
| rs11090045 | — | GWAS association (p=3.0e-18) | Meta-analysis |
| rs17671611 | — | GWAS association (p=3.0e-17) | Meta-analysis |
| rs12155745 | — | GWAS association (p=5.0e-17) | Meta-analysis |
| rs62081501 | — | GWAS association (p=6.0e-17) | Meta-analysis |
| rs7107356 | — | GWAS association (p=1.0e-16) | Meta-analysis |
| rs75614054 | PTCH1 | GWAS association (p=2.0e-16) | Meta-analysis |
| rs56084168 | BAIAP2 | GWAS association (p=3.0e-16) | Meta-analysis |
| rs4076453 | LINC02210-CRHR1 | GWAS association (p=3.0e-16) | Meta-analysis |
| rs1724422 | — | GWAS association (p=6.0e-16) | Meta-analysis |
| rs4587762 | — | GWAS association (p=6.0e-16) | Meta-analysis |
| rs9671386 | — | GWAS association (p=8.0e-16) | Meta-analysis |
| rs11608355 | — | GWAS association (p=2.0e-15) | Meta-analysis |
| rs1539844 | — | GWAS association (p=2.0e-15) | Meta-analysis |
| rs10502675 | — | GWAS association (p=2.0e-15) | Meta-analysis |
| rs6882046 | LINC00461 | GWAS association (p=3.0e-15) | Meta-analysis |
| rs34186148 | LINC02210-CRHR1 | GWAS association (p=4.0e-15) | Meta-analysis |
| rs1427041 | — | GWAS association (p=6.0e-15) | Meta-analysis |
| rs3785232 | — | GWAS association (p=8.0e-15) | Meta-analysis |
| rs655836 | — | GWAS association (p=8.0e-15) | Meta-analysis |
| rs1045430 | — | GWAS association (p=1.0e-14) | Meta-analysis |
| rs2186710 | — | GWAS association (p=1.0e-14) | Meta-analysis |
| rs7818437 | — | GWAS association (p=2.0e-14) | Meta-analysis |
| rs2071303 | HFE | GWAS association (p=2.0e-14) | Meta-analysis |
| rs35048193 | GRM8 | GWAS association (p=2.0e-14) | Meta-analysis |
| rs2042555 | — | GWAS association (p=2.0e-14) | Meta-analysis |
| rs11039182 | MADD | GWAS association (p=3.0e-14) | Meta-analysis |
| rs1501673 | MIR9-2 | GWAS association (p=3.0e-14) | Meta-analysis |
| rs7225384 | LINC02210-CRHR1 | GWAS association (p=3.0e-14) | Meta-analysis |
| rs3785237 | — | GWAS association (p=4.0e-14) | Meta-analysis |
| rs61572747 | — | GWAS association (p=5.0e-14) | Meta-analysis |
| rs2186800 | — | GWAS association (p=6.0e-14) | Meta-analysis |
| rs13054099 | — | GWAS association (p=7.0e-14) | Meta-analysis |
| rs1558804 | KCTD10 | GWAS association (p=7.0e-14) | Meta-analysis |
| rs722599 | PROX2 | GWAS association (p=8.0e-14) | Meta-analysis |
| rs72694269 | — | GWAS association (p=9.0e-14) | Meta-analysis |
| rs1806153 | — | GWAS association (p=2.0e-13) | Meta-analysis |
| rs61687445 | — | GWAS association (p=2.0e-13) | Meta-analysis |
| rs2488401 | — | GWAS association (p=3.0e-13) | Meta-analysis |
| rs4757136 | — | GWAS association (p=3.0e-13) | Meta-analysis |
| rs12344656 | LINGO2 | GWAS association (p=3.0e-13) | Meta-analysis |
| rs11576073 | — | GWAS association (p=3.0e-13) | Meta-analysis |
| rs2425752 | NCOA5 | GWAS association (p=5.0e-13) | Meta-analysis |
| rs1002655 | — | GWAS association (p=5.0e-13) | Meta-analysis |
| rs7025144 | — | GWAS association (p=6.0e-13) | Meta-analysis |
| rs7144654 | YLPM1 | GWAS association (p=6.0e-13) | Meta-analysis |
| rs10896636 | — | GWAS association (p=7.0e-13) | Meta-analysis |
| rs62064595 | — | GWAS association (p=7.0e-13) | Meta-analysis |
| rs10811883 | — | GWAS association (p=9.0e-13) | Meta-analysis |
| rs242947 | — | GWAS association (p=9.0e-13) | Meta-analysis |
| rs62550480 | — | GWAS association (p=1.0e-12) | Meta-analysis |
| rs10850137 | MYO1H | GWAS association (p=1.0e-12) | Meta-analysis |
| rs2407746 | — | GWAS association (p=2.0e-12) | Meta-analysis |
| rs1940709 | — | GWAS association (p=2.0e-12) | Meta-analysis |
| rs1438479 | — | GWAS association (p=2.0e-12) | Meta-analysis |
| rs12958048 | — | GWAS association (p=3.0e-12) | Meta-analysis |
| rs1644039 | LINC00461 | GWAS association (p=3.0e-12) | Meta-analysis |
| rs754593 | — | GWAS association (p=3.0e-12) | Meta-analysis |
| rs2435201 | MAPT | GWAS association (p=4.0e-12) | Meta-analysis |
| rs1563304 | — | GWAS association (p=5.0e-12) | Meta-analysis |
| rs2093623 | — | GWAS association (p=5.0e-12) | Meta-analysis |
| rs4632195 | — | GWAS association (p=5.0e-12) | Meta-analysis |
| rs2298489 | TTC12 | GWAS association (p=5.0e-12) | Meta-analysis |
| rs297343 | SOX6 | GWAS association (p=6.0e-12) | Meta-analysis |
| rs7396943 | ARNTL | GWAS association (p=6.0e-12) | Meta-analysis |
| rs836927 | — | GWAS association (p=7.0e-12) | Meta-analysis |
| rs12938775 | — | GWAS association (p=8.0e-12) | Meta-analysis |
| rs10119773 | — | GWAS association (p=8.0e-12) | Meta-analysis |
| rs2503775 | — | GWAS association (p=8.0e-12) | Meta-analysis |
| rs17151763 | — | GWAS association (p=9.0e-12) | Meta-analysis |
| rs11496294 | LOC105375974 | GWAS association (p=1.0e-11) | Meta-analysis |
| rs11039389 | — | GWAS association (p=1.0e-11) | Meta-analysis |
| rs1542212 | — | GWAS association (p=1.0e-11) | Meta-analysis |
| rs3751855 | — | GWAS association (p=1.0e-11) | Meta-analysis |
| rs4799936 | — | GWAS association (p=1.0e-11) | Meta-analysis |
| rs35864494 | GRM8 | GWAS association (p=1.0e-11) | Meta-analysis |
| rs56324019 | — | GWAS association (p=2.0e-11) | Meta-analysis |
| rs58271251 | — | GWAS association (p=2.0e-11) | Meta-analysis |
| rs608293 | PAX6 | GWAS association (p=2.0e-11) | Meta-analysis |
| rs7103648 | RAPSN | GWAS association (p=2.0e-11) | Meta-analysis |
| rs10942529 | TMEM161B-DT | GWAS association (p=2.0e-11) | Meta-analysis |
| rs17570807 | — | GWAS association (p=2.0e-11) | Meta-analysis |
| rs4360891 | — | GWAS association (p=2.0e-11) | Meta-analysis |
| rs1226574 | — | GWAS association (p=2.0e-11) | Meta-analysis |
| rs11214607 | — | GWAS association (p=3.0e-11) | Meta-analysis |
| rs761366 | — | GWAS association (p=3.0e-11) | Meta-analysis |
| rs78046549 | FAM120A | GWAS association (p=3.0e-11) | Meta-analysis |
| rs1472822 | — | GWAS association (p=3.0e-11) | Meta-analysis |
| rs11214629 | — | GWAS association (p=3.0e-11) | Meta-analysis |
| rs56403421 | — | GWAS association (p=5.0e-11) | Meta-analysis |
| rs1230106 | — | GWAS association (p=5.0e-11) | Meta-analysis |
Showing the top 100 of 1,169 variants by evidence strength.
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.