rs10896636
▶GWAS Catalog Trait Associations (5)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (5)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
educational attainment
Okbay A et al. “Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals.” Nature Genetics 54(4):437-449 (2022)
Allele C
OR 0.01
p 2.0e-17
N 3,037,499
Large GWAS
European
anxiety measurement
Thorp JG et al. “Symptom-level modelling unravels the shared genetic architecture of anxiety and depression.” Nature Human Behaviour 5(10):1432-1442 (2021)
Allele C
OR 0.02
p 7.0e-14
N 136,957
Large GWAS
European
neuroticism measurement
Nagel M et al. “Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.” Nature Genetics 50(7):920-927 (2018)
Allele C
OR 7.17
p 7.0e-13
N 449,484
Meta-analysisLarge GWAS
European
Nagel M et al. “Item-level analyses reveal genetic heterogeneity in neuroticism.” Nature Communications 9(1):905 (2018)
Allele C
OR 6.49
p 9.0e-11
N 380,506
Large GWAS
European
Luciano M et al. “Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism.” Nature Genetics 50(1):6-11 (2018)
Allele C
OR 6.52
p 7.0e-11
N 329,821
Large GWAS
European
Hill WD et al. “Genetic contributions to two special factors of neuroticism are associated with affluence, higher intelligence, better health, and longer life.” Molecular Psychiatry 25(11):3034-3052 (2020)
Allele C
OR 0.01
p 3.0e-9
N 270,059
Large GWAS
European
neurotic disorder
Cai N et al. “Minimal phenotyping yields genome-wide association signals of low specificity for major depression.” Nature Genetics 52(4):437-447 (2020)
Allele G
OR 0.01
p 3.0e-11
N 274,107
Large GWAS
European
major depressive disorder
Nagel M et al. “Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.” Nature Genetics 50(7):920-927 (2018)
Allele C
OR 5.96
p 3.0e-9
N 688,809
Meta-analysisLarge GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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