ARHGAP27
Rho GTPase activating protein 27
Summary
This gene encodes a member of a large family of proteins that activate Rho-type guanosine triphosphate (GTP) metabolizing enzymes. The encoded protein may pay a role in clathrin-mediated endocytosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2013]
Known Variants59 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs4763 | 17:43,471,489 | G/A | regulatory region variant | — |
| rs148792420 | 17:43,472,844 | G/A | — | uncertain significance |
| rs2509234098 | 17:43,472,889 | A/G | — | uncertain significance |
| rs747073880 | 17:43,473,197 | C/T | — | likely benign |
| rs62064597 | 17:43,473,307 | C/G | upstream gene variant | — |
| rs3169693 | 17:43,473,362 | G/T | — | uncertain significance |
| rs766669825 | 17:43,473,591 | G/C | — | uncertain significance |
| rs2509310434 | 17:43,473,620 | C/T | — | uncertain significance |
| rs371679665 | 17:43,473,868 | C/T | — | likely benign |
| rs755803083 | 17:43,473,925 | C/T | — | uncertain significance |
| rs2509364744 | 17:43,474,050 | C/G | — | likely benign |
| rs755192707 | 17:43,474,106 | G/C | — | uncertain significance |
| rs373045289 | 17:43,474,148 | C/T | — | likely benign |
| rs773861287 | 17:43,474,296 | G/A | — | likely benign |
| rs771562751 | 17:43,474,363 | C/G | — | uncertain significance |
| rs777125923 | 17:43,474,367 | C/G | — | likely benign |
| rs2509408423 | 17:43,474,377 | G/A | — | uncertain significance |
| rs62064598 | 17:43,474,668 | C/G | intron variant | — |
| rs1364402517 | 17:43,475,352 | G/A | — | uncertain significance |
| rs150663614 | 17:43,475,374 | C/T | — | uncertain significance |
| rs368752990 | 17:43,475,410 | G/A | — | uncertain significance |
| rs2509672323 | 17:43,480,081 | T/C | — | uncertain significance |
| rs151192753 | 17:43,481,401 | C/T | — | uncertain significance |
| rs1280120605 | 17:43,481,428 | C/T | — | uncertain significance |
| rs752975185 | 17:43,481,646 | C/G | — | uncertain significance |
| rs774633760 | 17:43,481,852 | C/G | — | uncertain significance |
| rs761754577 | 17:43,481,853 | C/G | — | uncertain significance |
| rs1215692427 | 17:43,481,876 | G/C | — | uncertain significance |
| rs974209180 | 17:43,482,293 | C/G | — | uncertain significance |
| rs1285604127 | 17:43,482,357 | G/A | — | uncertain significance |
| rs781404326 | 17:43,482,402 | C/A | — | uncertain significance |
| rs1192198575 | 17:43,482,439 | G/T | — | uncertain significance |
| rs1401021719 | 17:43,482,448 | G/C | — | uncertain significance |
| rs73984391 | 17:43,484,598 | G/A | — | — |
| rs62064641 | 17:43,488,792 | T/C | intron variant | — |
| rs12936645 | 17:43,495,420 | A/T | upstream gene variant | — |
| rs76344126 | 17:43,503,284 | G/A | regulatory region variant | — |
| rs767265337 | 17:43,506,859 | C/T | — | uncertain significance |
| rs754549838 | 17:43,506,882 | C/A | — | uncertain significance |
| rs2510307912 | 17:43,506,913 | C/T | — | uncertain significance |
| rs200604399 | 17:43,506,940 | G/A | — | uncertain significance |
| rs1450117737 | 17:43,506,951 | C/T | — | uncertain significance |
| rs2510310251 | 17:43,506,991 | G/C | — | uncertain significance |
| rs961465610 | 17:43,507,071 | G/C | — | uncertain significance |
| rs1380798216 | 17:43,507,086 | C/G | — | uncertain significance |
| rs1439013514 | 17:43,507,089 | G/A | — | uncertain significance |
| rs1467337883 | 17:43,507,155 | G/A | — | uncertain significance |
| rs990511751 | 17:43,507,183 | G/C | — | uncertain significance |
| rs917558326 | 17:43,507,185 | G/A | — | uncertain significance |
| rs1051728535 | 17:43,507,282 | C/T | — | uncertain significance |
| rs1404901715 | 17:43,507,292 | G/T | — | uncertain significance |
| rs12949256 | 17:43,507,297 | C/T | regulatory region variant | — |
| rs1195247891 | 17:43,507,317 | G/C | — | uncertain significance |
| rs2510322096 | 17:43,507,381 | C/G | — | uncertain significance |
| rs7220206 | 17:43,507,403 | G/A | regulatory region variant | — |
| rs1167392024 | 17:43,507,569 | C/T | — | uncertain significance |
| rs745759444 | 17:43,507,601 | G/T | — | uncertain significance |
| rs546150279 | 17:43,507,621 | C/T | — | uncertain significance |
| rs1169862160 | 17:43,507,627 | C/G | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.