rs77804065
This variant is located in the LINC02210-CRHR1 gene.
▶GWAS Catalog Trait Associations (5)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (5)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
forced expiratory volume
Schoeler T et al. “Combining cross-sectional and longitudinal genomic approaches to identify determinants of cognitive and physical decline.” Nature Communications 16(1):4524 (2025)
Allele C
OR 0.03
p 7.0e-55
N 373,397
Large GWAS
European
neuroticism measurement
Nagel M et al. “Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.” Nature Genetics 50(7):920-927 (2018)
Allele T
OR 11.69
p 1.0e-31
N 449,484
Meta-analysisLarge GWAS
European
Luciano M et al. “Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism.” Nature Genetics 50(1):6-11 (2018)
Allele T
OR 10.50
p 8.0e-26
N 329,821
Large GWAS
European
Headache
Meng W et al. “A Genome-Wide Association Study Finds Genetic Associations with Broadly-Defined Headache in UK Biobank (N=223,773).” Ebiomedicine 28:180-186 (2018)
Allele T
OR 0.01
p 6.0e-15
N 223,782
Major Consortium StudyLarge GWAS
European
alcohol consumption quality
Gelernter J et al. “Genome-wide Association Study of Maximum Habitual Alcohol Intake in >140,000 U.S. European and African American Veterans Yields Novel Risk Loci.” Biological Psychiatry 86(5):365-376 (2019)
Allele T
OR —
β 0.071
p 2.0e-12
N 143,965
Large GWAS
multi-ancestry
guilt measurement
Nagel M et al. “Item-level analyses reveal genetic heterogeneity in neuroticism.” Nature Communications 9(1):905 (2018)
Allele T
OR 6.18
p 6.0e-10
N 373,380
Large GWAS
European
About LINC02210-CRHR1
This locus represents naturally occurring readthrough transcription between neighboring genes CRHR1-IT1, CRHR1 intronic transcript 1 (Gene ID: 147081) and CRHR1, corticotropin releasing hormone receptor 1 (Gene ID: 1394) on chromosome 17. The readthrough transcript encodes a protein that shares sequence identity with the product of the CRHR1 gene. [provided by RefSeq, Dec 2016]
View all LINC02210-CRHR1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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