KCTD10
potassium channel tetramerization domain containing 10
Summary
The protein encoded by this gene binds proliferating cell nuclear antigen (PCNA) and may be involved in DNA synthesis and cell proliferation. In addition, the encoded protein may be a tumor suppressor. Several protein-coding and non-protein coding transcript variants have been found for this gene. [provided by RefSeq, Dec 2015]
Known Variants13 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs200627498 | 12:109,889,478 | G/C | — | uncertain significance |
| rs982623580 | 12:109,889,483 | C/T | — | uncertain significance |
| rs746468091 | 12:109,889,500 | C/T | — | uncertain significance |
| rs143606895 | 12:109,889,549 | G/A | — | uncertain significance |
| rs2500040066 | 12:109,894,057 | T/A | — | uncertain significance |
| rs2338104 | 12:109,895,168 | C/G | downstream gene variant | — |
| rs747613147 | 12:109,895,873 | G/T | — | uncertain significance |
| rs374251027 | 12:109,898,520 | C/T | — | uncertain significance |
| rs1212324249 | 12:109,898,526 | C/A | — | uncertain significance |
| rs1558804 | 12:109,898,732 | A/T | — | — |
| rs918106 | 12:109,904,318 | C/T | intron variant | — |
| rs6606725 | 12:109,905,368 | C/T | — | — |
| rs997187563 | 12:109,907,490 | G/A | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.