rs11653468

GWAS Catalog Trait Associations (4)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

Agents acting on the renin-angiotensin system use measurement

Allele A
OR 0.05
p 5.0e-12
N 237,530
Major Consortium StudyLarge GWAS
European

sex hormone-binding globulin measurement

Sinnott-Armstrong N et al. Genetics of 35 blood and urine biomarkers in the UK Biobank. Nature Genetics 53(2):185-194 (2021)
Allele A
OR 0.02
p 8.0e-12
N 322,484
Major Consortium StudyLarge GWAS
multi-ancestry

Calcium channel blocker use measurement

Allele A
OR 0.06
p 3.0e-9
N 204,378
Major Consortium StudyLarge GWAS
European
Sakaue S et al. A cross-population atlas of genetic associations for 220 human phenotypes. Nature Genetics 53(10):1415-1424 (2021)
Allele A
OR 0.06
p 3.0e-9
N 383,104
Large GWAS
multi-ancestry

HMG CoA reductase inhibitor use measurement

Allele A
OR 0.04
p 5.0e-9
N 290,385
Major Consortium StudyLarge GWAS
European
Sakaue S et al. A cross-population atlas of genetic associations for 220 human phenotypes. Nature Genetics 53(10):1415-1424 (2021)
Allele A
OR 0.04
p 5.0e-9
N 469,111
Large GWAS
multi-ancestry

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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