Trait
SNPs associated with HMG CoA reductase inhibitor use measurement
177 genetic variants across 58 genes have been associated with HMG CoA reductase inhibitor use measurement in published research. Key genes include ABCA1, ABCA6, ABCG8.
Associated variants177 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs12740374 | CELSR2 | GWAS association (p=2.0e-145) | Major Consortium Study |
| rs6511720 | LDLR | GWAS association (p=8.0e-116) | Major Consortium Study |
| rs964184 | APOA5 | GWAS association (p=6.0e-94) | Major Consortium Study |
| rs1367117 | APOB | GWAS association (p=9.0e-72) | Major Consortium Study |
| rs74617384 | — | GWAS association (p=3.0e-69) | Major Consortium Study |
| rs11591147 | PCSK9 | GWAS association (p=9.0e-64) | Major Consortium Study |
| rs4299376 | ABCG8 | GWAS association (p=7.0e-48) | Major Consortium Study |
| rs12916 | HMGCR | GWAS association (p=2.0e-46) | Major Consortium Study |
| rs140570886 | — | GWAS association (p=1.0e-41) | Major Consortium Study |
| rs10889338 | DOCK7 | GWAS association (p=3.0e-37) | Major Consortium Study |
| rs58542926 | TM6SF2 | GWAS association (p=2.0e-31) | Major Consortium Study |
| rs2519093 | ABO | GWAS association (p=7.0e-31) | Major Consortium Study |
| rs116881820 | TOMM40 | GWAS association (p=1.0e-30) | Major Consortium Study |
| rs7903146 | TCF7L2 | GWAS association (p=2.0e-30) | Major Consortium Study |
| rs2738447 | LDLR | GWAS association (p=5.0e-28) | Major Consortium Study |
| rs522761 | — | GWAS association (p=7.0e-26) | Major Consortium Study |
| rs1537371 | CDKN2B-AS1 | GWAS association (p=3.0e-25) | Major Consortium Study |
| rs2207132 | — | GWAS association (p=1.0e-24) | Major Consortium Study |
| rs15285 | LPL | GWAS association (p=3.0e-21) | Major Consortium Study |
| rs1169288 | HNF1A | GWAS association (p=4.0e-21) | Major Consortium Study |
| rs8126001 | — | GWAS association (p=2.0e-20) | Major Consortium Study |
| rs1495741 | — | GWAS association (p=1.0e-19) | Major Consortium Study |
| rs2287997 | — | GWAS association (p=3.0e-19) | Major Consortium Study |
| rs41289512 | — | GWAS association (p=1.0e-17) | Major Consortium Study |
| rs76895963 | — | GWAS association (p=3.0e-17) | Major Consortium Study |
| rs1501908 | — | GWAS association (p=7.0e-17) | Major Consortium Study |
| rs693668 | — | GWAS association (p=7.0e-17) | Major Consortium Study |
| rs77542162 | ABCA6 | GWAS association (p=6.0e-16) | Major Consortium Study |
| rs601338 | FUT2 | GWAS association (p=1.0e-15) | Major Consortium Study |
| rs6129760 | — | GWAS association (p=1.0e-15) | Major Consortium Study |
| rs79598313 | — | GWAS association (p=2.0e-15) | Major Consortium Study |
| rs4639414 | — | GWAS association (p=4.0e-15) | Major Consortium Study |
| rs1421085 | FTO | GWAS association (p=5.0e-15) | Major Consortium Study |
| rs1800588 | LIPC | GWAS association (p=2.0e-14) | Major Consortium Study |
| rs750332 | BAG6 | GWAS association (p=4.0e-14) | Major Consortium Study |
| rs9295123 | — | GWAS association (p=1.0e-13) | Major Consortium Study |
| rs10804330 | — | GWAS association (p=3.0e-13) | Major Consortium Study |
| rs112771035 | — | GWAS association (p=1.0e-12) | Major Consortium Study |
| rs7213086 | KPNB1 | GWAS association (p=2.0e-12) | Major Consortium Study |
| rs79701229 | — | GWAS association (p=6.0e-12) | Major Consortium Study |
| rs998584 | POLR1C | GWAS association (p=6.0e-12) | Major Consortium Study |
| rs2618567 | — | GWAS association (p=1.0e-11) | Major Consortium Study |
| rs12725767 | — | GWAS association (p=2.0e-11) | Major Consortium Study |
| rs3802932 | FERMT3 | GWAS association (p=2.0e-11) | Major Consortium Study |
| rs3918226 | NOS3 | GWAS association (p=7.0e-11) | Major Consortium Study |
| rs4518111 | — | GWAS association (p=9.0e-11) | Major Consortium Study |
| rs972283 | LOC105375508 | GWAS association (p=1.0e-10) | Major Consortium Study |
| rs11787365 | — | GWAS association (p=1.0e-10) | Major Consortium Study |
| rs645040 | — | GWAS association (p=2.0e-10) | Major Consortium Study |
| rs77673991 | — | GWAS association (p=2.0e-10) | Major Consortium Study |
| rs72837687 | LOC124903911 | GWAS association (p=3.0e-10) | Major Consortium Study |
| rs2066905 | MYLIP | GWAS association (p=4.0e-10) | Major Consortium Study |
| rs2737245 | TRPS1 | GWAS association (p=4.0e-10) | Major Consortium Study |
| rs268 | LPL | GWAS association (p=5.0e-10) | Major Consortium Study |
| rs10468017 | — | GWAS association (p=8.0e-10) | Major Consortium Study |
| rs10413278 | — | GWAS association (p=1.0e-09) | Major Consortium Study |
| rs73013176 | SMARCA4 | GWAS association (p=1.0e-09) | Major Consortium Study |
| rs3135064 | — | GWAS association (p=1.0e-09) | Major Consortium Study |
| rs17725246 | — | GWAS association (p=1.0e-09) | Major Consortium Study |
| rs11864054 | — | GWAS association (p=2.0e-09) | Major Consortium Study |
| rs4541244 | LINC01122 | GWAS association (p=2.0e-09) | Major Consortium Study |
| rs187429064 | TM6SF2 | GWAS association (p=2.0e-09) | Major Consortium Study |
| rs740516 | — | GWAS association (p=2.0e-09) | Major Consortium Study |
| rs13125101 | LOC124900725 | GWAS association (p=2.0e-09) | Major Consortium Study |
| rs112339942 | — | GWAS association (p=2.0e-09) | Major Consortium Study |
| rs11641811 | — | GWAS association (p=3.0e-09) | Major Consortium Study |
| rs34631598 | — | GWAS association (p=3.0e-09) | Major Consortium Study |
| rs577721086 | RSPO3 | GWAS association (p=3.0e-09) | Major Consortium Study |
| rs11743303 | C5orf67 | GWAS association (p=3.0e-09) | Major Consortium Study |
| rs11653468 | — | GWAS association (p=5.0e-09) | Major Consortium Study |
| rs2080227 | — | GWAS association (p=5.0e-09) | Major Consortium Study |
| rs3764261 | — | GWAS association (p=7.0e-09) | Major Consortium Study |
| rs1938598 | — | GWAS association (p=7.0e-09) | Major Consortium Study |
| rs570530 | — | GWAS association (p=7.0e-09) | Major Consortium Study |
| rs35430985 | — | GWAS association (p=7.0e-09) | Major Consortium Study |
| rs2603192 | TMPRSS11E | GWAS association (p=8.0e-09) | Major Consortium Study |
| rs799158 | MLXIPL | GWAS association (p=8.0e-09) | Major Consortium Study |
| rs2917677 | NQO1 | GWAS association (p=9.0e-09) | Major Consortium Study |
| rs2293093 | ACVRL1 | GWAS association (p=9.0e-09) | Major Consortium Study |
| rs73228424 | — | GWAS association (p=1.0e-08) | Major Consortium Study |
| rs7639816 | — | GWAS association (p=1.0e-08) | Major Consortium Study |
| rs221907 | — | GWAS association (p=1.0e-08) | Major Consortium Study |
| rs148566631 | — | GWAS association (p=2.0e-08) | Major Consortium Study |
| rs1030431 | — | GWAS association (p=2.0e-08) | Major Consortium Study |
| rs2982521 | — | GWAS association (p=2.0e-08) | Major Consortium Study |
| rs34850939 | — | GWAS association (p=2.0e-08) | Major Consortium Study |
| rs11057830 | SCARB1 | GWAS association (p=2.0e-08) | Major Consortium Study |
| rs146254843 | HPR | GWAS association (p=2.0e-08) | Major Consortium Study |
| rs66502159 | — | GWAS association (p=4.0e-08) | Major Consortium Study |
| rs12739394 | — | GWAS association (p=5.0e-08) | Major Consortium Study |
| rs57853403 | — | GWAS association (p=5.0e-08) | Major Consortium Study |
| rs10183431 | LRPPRC | GWAS association (p=5.0e-08) | Major Consortium Study |
| rs2068888 | — | GWAS association (p=7.0e-18) | Major Consortium Study |
| rs1260326 | GCKR | GWAS association (p=1.0e-39) | Major Consortium Study |
| rs2954021 | — | GWAS association (p=4.0e-88) | Major Consortium Study |
| rs1883025 | ABCA1 | GWAS association (p=1.0e-22) | Major Consortium Study |
| rs7412 | APOE | GWAS association (p=1.0e-276) | Major Consortium Study |
| rs61194703 | — | GWAS association (p=7.0e-119) | Large GWAS |
| rs13306206 | APOB | GWAS association (p=3.0e-118) | Large GWAS |
| rs2738464 | LDLR | GWAS association (p=7.0e-59) | Large GWAS |
Showing the top 100 of 177 variants by evidence strength.
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.