rs117763955
This is a intron variant variant in the ADGRB3 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
underweight body mass index status
Zhou JY et al. “Interaction of environmental factors with the polygenic risk scores of thinness-related genes in preventing obesity risk in middle-aged adults: The KoGES.” Journal of Human Nutrition and Dietetics : the Official Journal of the British Dietetic Association 36(4):1451-1467 (2023)
Allele T
OR 1.80
p 4.0e-8
N 22,912
Large GWAS
East Asian
About ADGRB3
This p53-target gene encodes a brain-specific angiogenesis inhibitor, a seven-span transmembrane protein, and is thought to be a member of the secretin receptor family. Brain-specific angiogenesis proteins BAI2 and BAI3 are similar to BAI1 in structure, have similar tissue specificities, and may also play a role in angiogenesis. [provided by RefSeq, Jul 2008]
View all ADGRB3 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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