ADGRB3
adhesion G protein-coupled receptor B3
Summary
This p53-target gene encodes a brain-specific angiogenesis inhibitor, a seven-span transmembrane protein, and is thought to be a member of the secretin receptor family. Brain-specific angiogenesis proteins BAI2 and BAI3 are similar to BAI1 in structure, have similar tissue specificities, and may also play a role in angiogenesis. [provided by RefSeq, Jul 2008]
Known Variants99 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs1352747885 | 6:69,348,666 | G/T | — | uncertain significance |
| rs1768012589 | 6:69,348,799 | C/T | — | uncertain significance |
| rs377083198 | 6:69,348,858 | A/C | — | uncertain significance |
| rs767760754 | 6:69,348,865 | G/T | — | uncertain significance |
| rs746699209 | 6:69,348,912 | G/T | — | uncertain significance |
| rs769247421 | 6:69,348,938 | A/G | — | uncertain significance |
| rs183409987 | 6:69,348,962 | G/A | — | uncertain significance |
| rs2481434781 | 6:69,349,007 | A/C | — | uncertain significance |
| rs148606686 | 6:69,349,084 | A/G | — | uncertain significance |
| rs750878276 | 6:69,349,132 | T/C | — | uncertain significance |
| rs894110065 | 6:69,349,163 | C/T | — | uncertain significance |
| rs1188135637 | 6:69,349,169 | A/G | — | uncertain significance |
| rs1338093306 | 6:69,349,199 | C/G | — | uncertain significance |
| rs2481435433 | 6:69,349,220 | T/C | — | uncertain significance |
| rs1768028005 | 6:69,349,277 | C/T | — | uncertain significance |
| rs2481435711 | 6:69,349,286 | G/T | — | uncertain significance |
| rs569446609 | 6:69,425,598 | A/G | — | — |
| rs72897202 | 6:69,427,093 | C/T | — | — |
| rs150728431 | 6:69,428,306 | G/A | regulatory region variant | — |
| rs571937506 | 6:69,445,569 | T/G | — | — |
| rs6931354 | 6:69,470,407 | G/C | — | — |
| rs10945141 | 6:69,470,709 | G/A | intron variant | — |
| rs542301662 | 6:69,478,372 | C/T | — | — |
| rs801262 | 6:69,524,373 | T/C | intron variant | — |
| rs545377989 | 6:69,543,683 | A/G | — | — |
| rs526156 | 6:69,556,840 | A/T | — | — |
| rs79541554 | 6:69,570,919 | C/T | intron variant | — |
| rs192812071 | 6:69,577,553 | C/T | intron variant | — |
| rs191933094 | 6:69,592,782 | T/G | intron variant | — |
| rs188653199 | 6:69,611,185 | C/A | regulatory region variant | — |
| rs17476005 | 6:69,615,493 | A/G | — | — |
| rs751392718 | 6:69,640,508 | A/T | — | uncertain significance |
| rs748456125 | 6:69,640,514 | G/C | — | uncertain significance |
| rs747355273 | 6:69,646,422 | G/A | — | uncertain significance |
| rs145733293 | 6:69,646,524 | G/A | — | uncertain significance |
| rs112210771 | 6:69,649,119 | G/A | intron variant | — |
| rs2481669900 | 6:69,653,751 | T/C | — | uncertain significance |
| rs371587255 | 6:69,653,877 | C/G | — | uncertain significance |
| rs186013318 | 6:69,666,006 | C/A | — | uncertain significance |
| rs1255428600 | 6:69,666,611 | A/C | — | uncertain significance |
| rs113677156 | 6:69,666,660 | C/T | — | uncertain significance |
| rs373283258 | 6:69,666,675 | G/A | — | uncertain significance |
| rs13191240 | 6:69,675,459 | T/C | intron variant | — |
| rs140623029 | 6:69,684,657 | C/A | — | uncertain significance |
| rs767292207 | 6:69,684,720 | G/A | — | uncertain significance |
| rs773250653 | 6:69,703,668 | G/T | — | uncertain significance |
| rs1380485443 | 6:69,703,705 | G/A | — | uncertain significance |
| rs1451989800 | 6:69,703,727 | C/T | — | uncertain significance |
| rs3798999 | 6:69,714,947 | A/G | intron variant | — |
| rs573044070 | 6:69,723,975 | G/A | — | uncertain significance |
| rs752178634 | 6:69,728,283 | A/G | — | uncertain significance |
| rs781711035 | 6:69,728,334 | A/G | — | uncertain significance |
| rs763335000 | 6:69,728,371 | A/G | — | uncertain significance |
| rs1889877 | 6:69,729,678 | G/A | intron variant | — |
| rs189008414 | 6:69,737,557 | G/A | intron variant | — |
| rs188980024 | 6:69,755,453 | T/C | intron variant | — |
| rs757620134 | 6:69,758,154 | G/T | — | uncertain significance |
| rs112866971 | 6:69,759,195 | G/A | — | uncertain significance |
| rs1562137453 | 6:69,759,199 | T/C | — | likely pathogenic |
| rs866124184 | 6:69,759,228 | C/G | — | uncertain significance |
| rs568012051 | 6:69,765,465 | A/T | — | — |
| rs2481874335 | 6:69,772,896 | T/C | — | uncertain significance |
| rs2343397 | 6:69,775,652 | T/C | — | — |
| rs191828137 | 6:69,819,174 | G/A | intron variant | — |
| rs190107978 | 6:69,831,486 | C/T | intron variant | — |
| rs148929237 | 6:69,845,424 | T/C | intron variant | — |
| rs314218 | 6:69,855,697 | C/T | intron variant | — |
| rs117050940 | 6:69,900,842 | G/A | — | — |
| rs754269130 | 6:69,943,214 | G/A | — | uncertain significance |
| rs370387606 | 6:69,943,244 | A/G | — | uncertain significance |
| rs779450 | 6:69,966,827 | A/G | intron variant | — |
| rs538885011 | 6:69,966,990 | G/A | — | — |
| rs6922214 | 6:69,968,484 | A/G | intron variant | — |
| rs780836754 | 6:69,973,863 | T/A | — | — |
| rs148413442 | 6:69,994,684 | C/T | intron variant | — |
| rs188406453 | 6:69,996,490 | C/T | intron variant | — |
| rs138549637 | 6:70,003,459 | T/C | intron variant | — |
| rs117763955 | 6:70,006,921 | C/T | intron variant | — |
| rs749339565 | 6:70,034,786 | C/T | — | uncertain significance |
| rs374356976 | 6:70,034,879 | G/A | — | uncertain significance |
| rs1413497432 | 6:70,037,779 | C/A | — | uncertain significance |
| rs1242459370 | 6:70,042,891 | A/T | — | uncertain significance |
| rs769568957 | 6:70,048,821 | C/A | — | uncertain significance |
| rs964837842 | 6:70,064,141 | G/A | — | uncertain significance |
| rs369475329 | 6:70,064,147 | G/A | — | uncertain significance |
| rs370962794 | 6:70,070,859 | C/A | — | uncertain significance |
| rs1356909090 | 6:70,070,955 | G/C | — | uncertain significance |
| rs757975932 | 6:70,071,057 | C/T | — | uncertain significance |
| rs749046588 | 6:70,071,198 | G/C | — | uncertain significance |
| rs375247005 | 6:70,071,203 | C/A | — | uncertain significance |
| rs746013983 | 6:70,071,214 | A/G | — | uncertain significance |
| rs76770231 | 6:70,071,244 | A/G | — | uncertain significance |
| rs3757057 | 6:70,074,232 | A/T | intron variant | — |
| rs189252626 | 6:70,086,504 | T/C | intron variant | — |
| rs1562005199 | 6:70,092,745 | G/A | — | likely pathogenic |
| rs761169898 | 6:70,092,751 | T/C | — | uncertain significance |
| rs180794638 | 6:70,093,713 | C/A | regulatory region variant | — |
| rs761863915 | 6:70,098,653 | C/T | — | uncertain significance |
| rs755846474 | 6:70,098,670 | A/G | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.