rs12193858
This is a intron variant variant in the ARMC2 gene.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
Uterine leiomyoma
Pujol Gualdo N et al. “Atlas of genetic and phenotypic associations across 42 female reproductive health diagnoses.” Nature Medicine 31(5):1626-1634 (2025)
Allele A
OR 1.08
p 2.0e-12
N 295,291
Large GWAS
European
hypothyroidism
Figuerêdo J et al. “Uncovering the shared genetic components of thyroid disorders and reproductive health.” European Journal of Endocrinology 191(2):211-222 (2024)
Allele T
OR 1.08
p 1.0e-10
N 691,986
Large GWAS
European
About ARMC2
Involved in sperm axoneme assembly. Implicated in spermatogenic failure 38. [provided by Alliance of Genome Resources, Jul 2025]
View all ARMC2 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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