rs12265047
▶GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
lung adenocarcinoma
Byun J et al. “Cross-ancestry genome-wide meta-analysis of 61,047 cases and 947,237 controls identifies new susceptibility loci contributing to lung cancer.” Nature Genetics 54(8):1167-1177 (2022)
Allele A
OR 0.18
p 2.0e-24
N 47,584
Meta-analysisLarge GWAS
multi-ancestry
lung cancer
Sato G et al. “Pan-cancer and cross-population genome-wide association studies dissect shared genetic backgrounds underlying carcinogenesis.” Nature Communications 14(1):3671 (2023)
Allele A
OR 0.83
p 2.0e-10
N 153,948
Large GWAS
East Asian
non-small cell lung carcinoma
Qin N et al. “Comprehensive functional annotation of susceptibility variants identifies genetic heterogeneity between lung adenocarcinoma and squamous cell carcinoma.” Frontiers of Medicine 15(2):275-291 (2021)
Allele G
OR 0.89
p 8.0e-10
N 54,475
Large GWAS
multi-ancestry
Dai J et al. “Identification of risk loci and a polygenic risk score for lung cancer: a large-scale prospective cohort study in Chinese populations.” The Lancet. Respiratory Medicine 7(10):881-891 (2019)
Allele G
OR 1.13
p 8.0e-10
N 54,475
Large GWAS
multi-ancestry
snoring measurement
Zhu Y et al. “A genome-wide association study based on the China Kadoorie Biobank identifies genetic associations between snoring and cardiometabolic traits.” Communications Biology 7(1):305 (2024)
Allele G
OR 0.08
p 4.0e-8
N 43,009
Large GWAS
East Asian
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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