rs12270146

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GWAS Catalog Trait Associations (3)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

body height

Schoeler T et al. “Combining cross-sectional and longitudinal genomic approaches to identify determinants of cognitive and physical decline.” Nature Communications 16(1):4524 (2025)

Allele A

OR 0.01

p 1.0e-11

N 405,540

Large GWAS

European

aortic stenosis, aortic valve calcification

Thériault S et al. “Integrative genomic analyses identify candidate causal genes for calcific aortic valve stenosis involving tissue-specific regulation.” Nature Communications 15(1):2407 (2024)

Allele G

OR —

p 8.0e-10

N 956,682

Large GWAS

European

C-reactive protein measurement

Said S et al. “Genetic analysis of over half a million people characterises C-reactive protein loci.” Nature Communications 13(1):2198 (2022)

Allele A

OR 0.01

p 1.0e-8

N 575,531

Large GWAS

European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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